Neuroanatomy 3 Flashcards

1
Q

How many lobes does the cerebellum have?

A

3 - anterior, posterior and flocculonodular

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2
Q

How does the cerebellum attach to the brainstem?

A

via 3 peduncles (‘feet’) - middle, superior, inferior

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3
Q

What separates the 2 hemispheres of the cerebellum?

A

Vermis (worm)

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4
Q

What are the 3 layers of the cerebelllar cortex?

A

Molecular layer (outer) - few neurones, lots of synapses
Purkinje layer
Granular layer - lots of neurones

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5
Q

Why is the granular layer of the cerebellar cortex a dark colour?

A

Because there is a vast number of neuones

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6
Q

Is the cerebellum a contralateral or ipsilateral organ?

A

Ipsilateral

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7
Q

What are the 3 functional units of the cerebellum?

A

Cerebrocerebellum - planning movements and motor learning
Spinocerebellum - regulating body movements, error correction and receives proprioceptive info
Vestibulocerebellium - controlling balance and occular reflexes

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8
Q

What would a unilateral hemispheric lesion in the cerebellum cause?

A

Disturbance in co-ordination in limbs, unsteady gait and intention tremor

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9
Q

What would a midline lesion in the cerebellum cause?

A

Disturbance of postural control

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10
Q

What would a bilateral cerebellar dysfunction cause?

A

Slowed, slurred speech (dysarthria)
Bilateral inco-ordination of arms
Staggering, wide-based gait (cerebellar ataxia)

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11
Q

What are the functions of the basal ganglia?

A

Facilitate purposeful movement
Inhibit unwanted movements
Posture and muscle tone

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12
Q

What are the basal ganglia?

A

A number of masses of grey matter found at the base of each cerebral hemisphere

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13
Q

What are the 5 basal ganglia?

A
Caudate nucleus
Putamen
Globus pallidus
Subthalamic nucleus
Substantia nigra
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14
Q

What makes up the lenticular nucleus?

A

Putamen

Globus pallidus

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15
Q

What makes up the striatum?

A

Caudate nucleus

Putamen

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16
Q

What makes up the corpus striatum?

A

Caudate nucleus
Putamen
Globus pallidus

17
Q

Where is the amydala situated?

A

On the end of the caudate nucleus

18
Q

Where is the substantia nigra found?

A

Midbrain

19
Q

Why is the substangia nigra black?

A

Dopaminergic neurones

20
Q

How do basal ganglia affect normal movement?

A

They enhance it

21
Q

What is meant by the direct pathway of basal ganglia?

A

Net effect of exciting thalamic neurones

22
Q

What is meant by the indirect pathway of basal ganglia?

A

Net effect of inhibiting thalamic neurones i.e. stops unwanted muscle contractions from competing with voluntary movements

23
Q

What would a unilateral lesion of basal ganglia cause?

A

Affects the CONTRALATERAL side
Change in muscle tone
Dyskinesias e.g. tremor, chorea, myoclonus

24
Q

What diseases affect basal ganglia?

A

Parkinsons

Huntingtons