Neuro/somatic symptom/sleepwake Flashcards
What is the most effective treatment for primary enuresis?
enuresis alarm
What is the level of control and motivation in these 3 disorders? (conscious vs unconscious)
1. Somatic symptom disorders
2. Factitious disorders
3. Malingering
- Somatic symptom disorders: unconscious control, unconscious motivation
- Factitious disorders: conscious control, unconscious motivation
- Malingering: conscious control, conscious motivation
Compare children’s sleep to adults.
__ REM (more/less)
__ REM (earlier/later)
__ REM (more frequent, less frequent)
__ total hrs of sleep
More REM
Earlier REM
More frequent REM
More total hrs of sleep
Which nucleus of the hypothalamus regulars sleep?
Suprachiasmatic nucleus
Which part of sleep do you see the following activity on EEG?
A) alpha activity, vertex waves
C) K complexes w/sleep spindles or bundles
D) high amplitude delta (slow) waves
E) saw tooth waves
A) N1 sleep & when awake with eyes closed, drowsy twilight sleep
C) N2 sleep (light NREM sleep)
D) N3 sleep (deep, slow wave NREM sleep)
E) REM sleep
What is the progression of sleep cycle over 90 mins?
N1 –> N2 –> N3 –> N2 —> REM
Multiple sleep latency test is useful to assess for what dx?
Narcolepsy
Are Zolpidem and Zaleplon for sleep initiation or sleep maintenance?
sleep initiation
Is Suvorexant for sleep initiation or sleep maintenance?
sleep maintenance
What hormone secreted by pineal gland regulates circadian rhythm?
Melatonin
Psychostimulants such as Dextroamphetamine, Methylphenidate, Modafinil, Armodafinil and Selegiline are used to tx what sleep disorder?
hypersomnolence disorder and narcolepsy in daytime
Low hypocretin-1 (aka orexin) in the CSF is found in what sleep disorder?
Narcolepsy
REM latency < 15mins, mean sleep latency <8mins and 2 or more sleep onset REM periods found on nocturnal sleep polysomnography is aligned with what sleep d/o?
narcolepsy
Which sleep medication is contraindicated in narcolepsy b/c it is a orexin receptor antagonist?
Suvorexant
Narcolepsy has ___ % monozygotic twin concordance?
30%
What hypnotic can you give in the nighttime for tx of narcolepsy?
sodium oxybate: CNS depressant that increases N3 sleep
Sodium oxybate activates what receptor?
GABA-B receptor
For what category of sleep disorders are Modafinil and armodafinil helpful with? (3 disorders)
promoting daytime wakefulness
Narcolepsy
OSA
Shift work sleep disorder