Neuro Review Flashcards
What is bacterial meningitis?
Inflammation of meninges secondary to bacterial infection
Causes of bacterial meningitis
Hemorrhagic spread, foreign body migration, extension of otitis media/interna (majority of cases), traumatic or iatrogenic inoculation
Diagnosis of bacterial meningitis
Clinical presentation, routine blood work, MRI (meningeal contrast enhancement), CSF (marked neutrophilic pleocytosis with intracellular bacteria, can be normal in chronic cases, only 33% bacterial growth), pyrexia only in 13% of cases
Prognosis of bacterial meningitis
Good prognosis (83% survival to discharge), with few/mild long-term neurological deficits.
Decerebrate
Extensor rigidity in all 4 limbs, patient comatose.
Severe midbrain lesion.
Poor to grave prognosis.
Decerebellate
Opisthotnus, flexed pelvic limbs.
Acute cerebellar lesion.
Better prognosis than decerebrate.
Menace
Afferent: ipsilateral CNII, contralateral thalamus and occipital cortex
Efferent: contralateral motor cortex, ipsilateral cerebellum, ipsilateral CN VII
PLR
Midbrain
Afferent: CN II
Efferent: CN III parasympathetic
Trigeminofacial reflex
Palpebral, vibraase, lip pinch
PONS
Afferent: CN V
Efferent: CN VII
Corneal reflex
PONS
Afferent: CN V (ophthalmic branch)
Efferent: CN VII (globe retraction, CN VII (Blink))
Physiologic nystagmus
PONS, midbrain
Afferent: CN VIII
Efferent: CN III, IV, VI
Gag reflex
Medulla
Afferent: CN IX, X
Efferent: CN IX, X, XII
Reactive Seizure
The normal brain’s natural response to a transient disturbance in function, usually metabolic or toxic in nature. Is usually reversable when the inciting cause is removed or corrected (i.e. hypoglycemia)
Epileptic Seizure
A manifestation of excessive synchronous epileptic activity of neurons in the brain.
Epilepsy
Recurrent seizures of at least two unprovoked epileptic seizures (of any type) in a 24-hour period, resulting from a disease in the brain causing a predisposition to generate epileptic seizures.