neuro pt1 Flashcards

1
Q

how much does the brain consume

A

25% of body’s oxygen
25% of body’s nutrients
70% of body’s glucose

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2
Q

what does 1-60 seconds of no blood flow to the brain cause

A

loss of conciousness

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3
Q

what does 2-4 seconds of no blood flow to the brain cause

A

glycogen and glucose stores are exhausted

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4
Q

what does 4-5 minutes of no blood flow to the brain cause

A

cellular ATP stores are fully depleted, brain damage likely

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5
Q

what does 6-10 minutes of no blood flow to the brain cause

A

brain damage is likely

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6
Q

what does 10+ minutes of no blood flow to the brain cause

A

irreversible brain damage (biological death)

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7
Q

what are the four types of brain insults

A

ischemia insults
acute insults
increased intercranial pressure (insults)
degenerative disorders (insults)

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8
Q

what is global ischemia

A

blood flow cannot meet metabolic demands (cardiac arrest, shock, asphyxiation)
to entire brain

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9
Q

what is focal ischemia

A

ischemia to one focal or specific portion of the brain (strokes)

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10
Q

true or false: 25% of strokes happen in people with history of previous strokes

A

true

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11
Q

what are the categories of ischemic strokes

A

thrombus (disease)
embolisms (clots)
hypoxia (an event)

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12
Q

what is a hemorrhagic stroke categorized as? idk

A

primary brain bleed

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13
Q

how many internal carotid arteries are there and where are they located

A

two
come up laterally from the front of the neck, branch off into two terminal arteries

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14
Q

what do the external carotid arteries do

A

supply blood to the neck and face

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15
Q

how many vertebral arteries are there and where are they located

A

two
come up laterally along the spine and near the back of the neck

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16
Q

what do vertebral arteries do

A

supplies blood to the brain stem and, cerebella and occipital lobes

17
Q

the two vertebral arteries come together and form what

A

basilar arteries

18
Q

what arteries anastomose (join) each other at the base of the brain and what does it form

A

basilar and internal carotid arteries
forms circle of willis

19
Q

what does the circle of willis connect

A

anterior posterior brain circulation
(if one artery is damaged, blood flow is usually not compromised)

20
Q

what is a thrombolytic stroke

A

most common of ischemic strokes
local action
build up of plaque
atherosclerosis (carotids/vertebral)

21
Q

what is an embolic stroke

A

clot originates somewhere in the body and travels to the brain
may be secondary to thrombotic stroke (embolus detached from primary site of stroke)

22
Q

what is a large vessel thrombotic occlusion (LVO)/strokes

A

large vessel disease (atherosclerosis)
counts for 20% of ischemic strokes
symptoms vary with location

23
Q

what are “occlusions” but not necessarily clots yet

A

middle cerebral artery (MCA) most common
anterior cerebral artery (ACA) least common
posterior cerebral artery (PCA)
vertebral/basilar (basilar) artery

24
Q

what is a cerebral “small vessel disease”/thrombotic stroke

A

25% of ischemic strokes
small arteries sometimes called small strokes or lacunar infarctions
usually small and deep
closely linked to hypertension
likely a form of atherosclerosis
“white matter hyperintensity” or “white matter disease”

25
Q

what do cerebral “small vessel disease”/thrombotic strokes cause

A

loss of function
disability
age-related cognitive decline related to dementia, strokes, motor movement issues (old)

26
Q

what is a transient ischemic attack (TIA)

A

“short-lives/passing/temporary” form of brain ischemia
symptoms caused by cellular hypoxia without cellular death, thus NOT a “mini stroke”
warning sign of a real stroke
15% experience full strokes within 3 months

27
Q

what is a warning sign of transient ischemic attack (TIA)

A

hypoxia without severe damage

28
Q

what are the cardiogenic sources of ischemic strokes

A

20%
atrial fibrillation
myocardial infarction
endocarditis
other dysrhythmias

29
Q

what are the other and unusual (unknown) causes of ischemic strokes

A

35%
vasospasm after subarachnoid hemorrhage
cerebral vasoconstriction syndromes
radiation-induced vasculopathy
air or fat embolisms
amniotic fluid following childbirth
tumors
unknown

30
Q

true or false: in the acute stages a stroke is stagnant

A

false: it is evolving, will not know true outcomes for person for days/weeks

31
Q

what are the causes and risk factors for ischemic strokes

A

• Like cardiovascular disease
• Uncontrolled HTN
• Smoking
• Heart disease/atherosclerosis
• Diabetes
• Atrial fibrillation
• Carotid artery disease/stenosis
• Hyperlipidemia
• Physical inactivity/obesity
• Eclampsia in pregnancy

32
Q

what is a hemorrhagic stroke

A

burst of blood vessel may allow blood to seep into and damage brain tissues until clotting shuts off the leak

33
Q

what is the process of a brain hemorrhage

A
  1. Rupture of a blood vessel (aneurysm?)
  2. Bleeding goes into the brain (location matters)
  3. Creates a focal hematoma that may get larger,
  4. The brain swells
  5. Brain matter gets compressed
  6. coma/death
34
Q

what are the symptoms of a hemorrhagic stroke

A

Person feels a “thunderclap headache”
Contralateral hemiplegia
Leads to spasticity
Loss of consciousness
Increased intracranial pressure
Coma/posturing/death (without treatment)

35
Q

what do primary injuries of strokes result from

A

compression by the hematoma
increase in the intracranial pressure