Neuro physio Flashcards
Creates myelin in CNS
Oligodendrocytes
Schwann cells in PnS
Unmyelinated portions of axons
Nodes of ranvier
Where action potential in neuron starts
Axon hillock
Terminal portion that contains vesicles with neurotransmitter
Terminal bouton or end feet or axon terminal
Death of axon distal to the site of injury after an axon is transected
Wallerian or anterograde or orthograde degeneration
Purpose of retrograde axonal transport
Recycles synaptic vesicle membrane for lysosomal degradation
Which NT is deficient in Alzheimer disease
Ach
Dopamine is degraded by ________ in presynaptic nerve terminals
MAO
COMT In liver
Which part of the pons secretes norepinephrine
Locus ceruleus
Serotonin Is secreted mainly by ________
Median raphe of brain stem
Serotonin is derivative of which AA
Tryptophan
Melatonin Serotonin niacin
Serotonin is converted to __________ in the pineal gland
Melatonin
Nitric oxide: inhibitory. True or false?
True!
Derived from arginine
Histamine is found mainly in the
Tuberomamillary nucleus of the hypothalamus
Number one inhibitory NT in the brain
GABA
RMP
-70mV
Main contributor to RMP
Nernst Potential
Membrane potential at which action potential is inevitable
Threshold
Depolarization is caused by
Na influx to the cell via opening of sodium activation gates
Repolarization is caused by
K+ efflux –> inside of the cell more negative
Two or more presynaptic inputs arrive simultaneously
Spatial Summation
Two or more presynaptic inputs arrive in rapid or successive fashin
Temporal summation
Nerve fiber for slow pain and temperature
Type C
Lesions in __________ cause anterograde amnesia
Hippocampus
Lesions in ________ cause retrograde amnesia
Thalamus
Loss of pre existing memories
Satiety center
Ventromedial nuclei
Sweating
Anterior hypothalamus
Master clock
Suprachiasmatic nucleus
True or false: melatonin decreased by darkness
False!
Increased by darkness
Inhibited by daylight
Secretion of muramyl peptide causes _______
Sleep
______ waves are predominant in REM sleep
Beta
Stage 2 sleep characterized by
Theta waves
Sleep spindles
K complexes
Sympathetic preganglionic neuron
Thoracolumbar distribution
Para is craniosacral
Effect of sympathetic NS on bronchioles
Dilates via B2 receptors
NT on all preganglionic neurons
Acetylcholine
Parasympathetic cranial nerves
CN X IX VII III
10973
No parasympathetic fibers in these organs
Ventricles of heart
Almost all blood vessels
Pregnant uterus
Renin secretion is mediated by _________ NS
Sympathetic
Contraction of radial muscle cause _______
Mydriasis –> increase pupil size
Miosis is caused by _______ NS due to contraction of ________
Parasympathetic NS
Contraction of circular muscle
Contraction of CILIARY muscle is for _______ vision and mediated by _________ NS
Near vision
Parasympathetic
B3 receptor found in
Brown fat
Macrophage of brain
Microglia