Blood Physiology Flashcards
components of heme
protoporphyrin IX and Fe2
Where is iron mostly absorbed?
Duodenum
Last stage of RBC with a nucleus
Orthochromatic Erytrhoblast
Form of RBC released to the blood
Reticulocytes
Lifespan of fetal RBC
90 days
Fate of heme in destroyed RBCs
Bilirubin
1st line of defense
Innate immunity
Lifespan of granulocytes
4-8 hours in blood
4-5 days in tissues
Most common WBC
Neutrophils
Bilobed nucleus, stain bright red with eosin dye
Eosinophils
Lifespan of platelets
7-10 days
WBC involved in adaptive immunity
Lymphocytes
Movement of neutrophils and macrophages out of the circulatory system and into the site of injury
Diapedesis
What substance is released by mast cells that cause vasodilation and increased vascular permeability
Histamine
What portion of antibodies are determines specificity to antigen
Variable portion
Smallest Ig
IgG
Ig able to cross placenta
IgG
Largest Ig and present on all uncomitted B cells
IgM
Complement for opsonization
C3b
Complement that is chemotactic to WBCs
C5a
Membrane Attack complex
C5b-C9
Which T cells are capable of creating perforins
cytotoxic T cell
Type D antigen is widely prevalent
Rh
Responsible for platelet adhesion
vWF
Glycoprotein 1b