Neuro Oncology Flashcards
1
Q
MC brain tumors?
A
#1-mets MC primary= astrocytomas
2
Q
What are the three main types of astrocytomas?
A
- pilocytic
- anaplastic
- glioblastoma
3
Q
Pilocytic astrocytoma:
- gross appearance
- microscopic appearance
- age group
A
- cystic, around ventricles vs cerebellum
- Rosenthal fibers (red worms)
- children or young adults
4
Q
Which glioblastoma is most malignant?
A
-glioblastoma, shockingly, NOT anaplastic
5
Q
Anaplastic astrocytoma:
- microscopic appearance
- life expectancy
A
- ^^ cells, mitoses, abnormal nuclei
- less than five years
6
Q
Glioblastoma:
- presentation
- age group
- survival rate
A
- seizures, focal deficit
- 5th-7th decades
- survival 12-18 months
7
Q
Glioblastoma:
- microscopic appearance
- gross appearance
A
- pseduopalisading necrosis
- butterfly (crosses corpus), ring enhancing
8
Q
Oligodendrogliomas:
- presentation
- age group
- life expectancy
A
- seizures
- 4th-5th decade
- 5-10 years (can resect + chemo)
9
Q
Oligodendrogliomas:
- location
- microscopic appearance
A
- supratentorial**
- fried egg appearance
10
Q
Ependymomas:
- age group
- presentation
A
- children –> young adults
- headaches + vision changes especially in the morning
11
Q
Ependymomas:
- microscopic appearance
- gross location
A
- perivascular pseudorosettes
- fourth ventricle vs spinal cord (can be supra OR infratentorial)
12
Q
MC spinal cord glioma?
A
ependymoma
13
Q
Primitive Neuroectodermal Tumors:
general appearance
A
small round blue cells
blastomas
14
Q
MC intracranial PNET
A
medulloblastoma
15
Q
Medulloblastoma:
- location
- complication
- age group
A
- cerebellum
- drop mets to spinal cord
- children