Headache Flashcards
Cranial structures not sensitive to pain (4)
- ventricles
- choroid
- parenchyma (-midbrain)
- small veins
Part of midbrain sensitive to pain
dorsal raphe nucleus
Three main headache groups
- primary
- secondary
- cranial neuralgia
Migraine pathophysiology: l
- begin in brainstem
- trigeminal system activation
- activation of chemoreceptors and autonomic nervous system
How common is aura in migraine?
-60-70% of migraines
Describe complicated migraine
-long dramatic aura, may mimic stroke
Basilar migraine:
- location
- assc symptoms
- occipital throbbing pain
- vertigo, dysarthria, ataxia
Contrast bickerstaffs migraine and simple basilar migraine
-bickerstaffs begins with total blindness
List four abortive therapies for migraines
- NSAIDs
- Triptans
- DOPA antagonists
- Combos
Which triptan is short acting? long acting?
- sumatriptan: short
- zolmi: intermediate
- frova: long
List the two dopa antagonists for migraines
- metoclopramide (reglan)
- prochlorperazine (Compazine)
When is migraine prophylaxis needed?
- migraines 3+ times per month
- functional impairment
List five drug classes used for migraine prophylaxis
- BBers
- CCBs
- TCAs
- Anticonvulsants
- Serotonergic Drugs
List the four anticonvulsant drugs for migraine prophylaxis:
- keppra: leviteracetam
- Depakote: valproic acid
- Topamax: topiramate
- Neurontin: gabapentin
Describe cluster headache
severe unilateral stabbing periorbital/ temporal pain
Pathway involved in cluster headache pathogenesis:
-trigeminal-hypothalamic pathway
How is O2 administered for cluster H/A?
-12L/min for 15 mins
Prophylactis for cluster HA
- steroids
- CCBs
1 HA disorder
tension headache
Tension H/A never includes:
-N/V
Abortive therapy tension HA
- Acetaminophen
- NSAIDs
Prophylaxis tension HA
- TCA
- gabapentin
Drugs assc with idiopathic intracranial hypertension
- TCN
- OCPs
- vitamin A
How should LP be done in IIH?
-lateral decubitus position
Two treatments for IIH (drug)
- acetazolamide
- topiramate
Warning signs for headache:
-three types
- worst ever
- first severe
- subacute worsening
Warning signs for headache:
-five assc symptoms
- abnormal exam
- fever
- vomiting
- worsening with bending/lifting/coughing
- disturbs sleep
Warning signs for headache:
age
-55+