Neuro

Question 1

Bilateral proximal muscle weakness + dysphagia Purple rash on cheek

Answer 1

Polymyositis

Question 2

Bilateral dilated pupils + anticholinergic signs (increase pulse, low BP, urinary retention)?

Answer 2

TCA overdose

Question 3

Main complication of meningitis?

Answer 3

Sensorineural hearing loss

Question 4

What are you at risk of with neurofibromatosis type one

Answer 4

phaeochromocytoma

Question 5

Proximal myopathy DDx:

Answer 5

Endocrine (Hypo/hyper T4/PTH, Cushing’s, acromegaly); Infection (HIV), Drugs (Amiodarone, corticosteroids, cocaine), Muscular dystrophies (becker’s), NMJ (MG, Lambert Eton); Rheum (polymyalgia rheumatica, polymyositis, dermatomyositis SLE, RA)

Question 6

Peripheral neuropathy DDx:

Answer 6

Motor loss: GBS, chronic inflammatory demyelinating polyneuropathy (CIDP), porphyria, lead poisoning, hereditary sensorimotor neuropathies (CMT) Infection: dipthera; Sensory loss: DM, Alcohol(sensory first), B12 deficiency (affect joint position + vibration), Amyloidosis, uraemia(CKD), leprosy