Neuro Flashcards
What are the characteristic features of NF1?
Cafe-au-lait spots Macrocephaly Feeding problems Short stature Learning disabilities
Later, they develop:
Fibromas
Neurofibromas
Other tumors
What are the characteristic features of NF2?
Bilateral acoustic neuromas
Cataracts
What is Alteplase?
IV Thrombolytic
Give within 3.5 - 4 hours of stroke symptom onset
A patient is on ASA therapy and has a stroke anyway. What do you give them?
ASA
+
Dipyridamole or Clopidogrel
CGG’ trinucleotide repeat expansions are associated with
Fragile X Syndrome
Syndrome: ADHD features Autism-like features Speech delay Motor delay
Head abnormalities
Macroorchidism
Fragile X Syndrome
Arachnodactyly
Long slender fingers
Most commonly found in Marfan Syndrome
Marfan Syndrome
Tall Thin Ectopia Lentis Pectus Carinatum Aortic Root Dilation
Internuclear Ophthalmoplegia
Affected eye can’t adduct
Contralateral eye abducts with nystagmus
Accommodation intact
From damage to MLF
If bilateral, it is likely MS
Bilateral MLF Lesions
Bilateral Internuclear ophthalmoplegia
Classically seen in MS
Unilateral MLF Lesion
Unilateral internuclear ophthalmoplegia
Lacunar stroke in pontine artery distribution
Damaged Edinger-Westphal Nucleus
Interrupted Preganglionic Parasympathetic outflow to the eye
Ipsilateral fixed dilated pupil nonreactive to light or accommodation
Common complication in premature and underweight neonates
Interventricular hemorrhage
Blood in subarachnoid space impairs arachnoid villi from absorbing CSF
Leads to communicating hydrocephalus
2 Components of Occulomotor Nerve
Inner Somatic Fibers - Levator, EOMs
Superficial Parasympathetic Fibers - Iris Sphincter, Ciliary Muscles
Ischemic CN III Injury
Inner somatic fibers are further from blood supply
Ptosis + Down-and-Out
Preserved pupillary response (this is compromised in compressive neuropathy)
(Microvascular complication from diabetes)
What age is normal for breath holding spells?
6 months to 2 years
Management of breath holding spells
Reassurance - Does not affect development
Some will stop by age 5
Some will develop vasovagal syncope later in life