Neuro Flashcards

1
Q

Antiepyleptics that fuck with the pill

A

Phenytoin Carbemazapine definitely do by enhancing enzymes reducing effectiveness

Lamotrigine is a maybe because it is non enzyme enducing but the pill might lower the Lamotrigine levels and the Lamotrigine might lower oestrogen levels

topiremate - barbituate

Sodium valproate is safe

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2
Q

LP findings in MS

A

oligoclonal bands

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3
Q

LP indications

A

CS infection
subarachnoid
raised ICP
idiopathic intercranial hypertension - this one is therapeutic, tap every now and then

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4
Q

idiopathic intercranial hypertension

A

acetozolamide

LP tap every now and then

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5
Q

end of spinal cord

A

L1 L2

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6
Q

where to do LP

A

l3/4 or l4/5

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7
Q

how do you tell traumatic tap or subarach

A

usually you take 3-4 taps. do a 5th . if massive discrepency between first cells and 5th cells then trauma is cause and take the second result

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8
Q

GCS of 8 is protect airway and defined as coma

A

8

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9
Q

MS autoantibody or T cell mediated

A

T cell

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10
Q

types of MS in order commoness

A

relapsing remitting
primary progressive
relapsing progressive

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11
Q

LHermittes sign

A

flex neck electric shock

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12
Q

optic neuritis symptoms

A

pain on moving eyes and visual bluriness

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13
Q

where does MS start

investigations

A

legs

MRI T2 new lesions T1 old lesions. enhance with gandolinium contrast

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14
Q

acute relapse of ms treat:

A

steroid

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15
Q

preventer in active phase

A

fingolimod prevents and natalizumab does t cells

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16
Q

berry aneurysm repair

A

surgical clip or coil

17
Q

temporal lobe epilepsy

A

epigastric rising, deja vu, automatism, olfactory symptoms

18
Q

frontal

A

jaxonian march, one hand posturing

19
Q

most common cause of temporal lobe epilepsy

A

hippocampal sclerosis

20
Q

temporal lobe epilepsy type of seizure

A

partial

21
Q

generalised seizures treat

A

sod val, leviteracetam(cepra), lamotrigine ,carbemazipine

22
Q

prophylaxis migraine

A

b blocker, pizotifl which is 5HT2 antagonist

23
Q

memantine mechanism

A

NMDA receptor antagonist

24
Q

absence seizures

A

ethosuximide

25
Q

partial seizures treat

A

carbemazipine

26
Q

status epilepticus

A

rectal diazepam, buccal midazolam, if iv access start with iv lorazepam if not work phenytoin infusion, phenobarb if you think they alcoholic give thiamine via pabrenax if still no work give general

27
Q

dorsiflexion nerve root

A

L5

28
Q

knee flexion

A

L5, S1

29
Q

median nerve muscles

A

LOAF

30
Q

ulnar muscles

A

HILA

31
Q

trigeminal neuralgia treat

A

carbemazipine

32
Q

myasthenia gravis

A

autoantibodies against NMJ, edrophonium, diagnostic test with atropine to stop having bradychardia.

pyridostigmine is treatment
myasthenia crisis is resp failure

33
Q

CPP =

A

MAP - ICP

34
Q

CBF =

A

CPP/CVR