Neuro 2 Flashcards
Criteria for epilepsy diagnosis
- two or more unprovoked seizures occur
- one seizure occurs in a person whose risk of occurrence is at least 60%
- one or more seizures occur in context of known epilepsy syndrome
Top five RF for seizure disorder?
head trauma, stroke, infectious disorders, toxic-metabolic disorders, drug and alcohol withdrawal
Primary neurologic disorders related to seizures:
benign febrile convulsions of childhood, idiopathic/cryptogenic seizures, cerebral dysgenesis, symptomatic epilepsy
Treatment of eclampsia
magnesium sulfate
What is porphyria?
disorder of heme synthesis, produces neuropathies and seizures
Treatment of porphyria
gabapentin, pregabalin, levetiracetam
Drug toxicity and drug withdrawal typically results in what type of seizure?
generalized tonic-clonic
Unusual drug that causes seizures?
isonazid
When does EtOH withdrawal occur?
within 48 hours of cessation and resolves within 12 hours
When does sedative withdrawal occur?
within 2-4 days, but can be delayed to 1 week
At what age do benign febrile convulsions occur?
6 months to 5 years
When do benign febrile convulsions occur?
first day of a febrile illness (temp >100.4)
How long do seizures of benign febrile convulsions occur?
10-15 minutes and lack focal features
Treatment for benign febrile convulsions?
usually self-limited; can treat with diazepam or buccal midazolam; for recurrences–intermittent oral diazepam at onset of febrile illness
Idiopathic seizures account for x of all new -onset seizures
2/3
Seizures within x week after non-penetrating injury are not predictive of a chronic seizure disorder
first week
seizures are more commonly seen with hemorrhagic or ischemic stroke?
hemorrhagic
Non-epileptic seizures are generally what type?
general tonic-clonic with warning
What differentiates non-epileptic seizures?
No LOC, no postictal confusion, EEG does not show organized seizure activity
If a seizure/spell event occurs with flaccid unresponsiveness what is likely?
hypoperfusion
If flaccid unresponsiveness due to hypoperfusion is prolonged it can lead to brief stiffening or jerking, called:
convulsive syncope
Post-ictal state follows what type of seizure?
generalized tonic-clonic
A prolonged postictal state follows what type of seizure?
status epilepticus
Tongue biting is indicative of what type of seizure?
gernalized tonic-clonic