MSK Quiz 2: Part 2 Flashcards
What does diarthroses mean?
freely movable
Where is the synovial fluid secreted from?
synoviocytes
what’s the job of the synovial fluid?
nourishes the articular cartilage, shock absorber
What’s the most common of all joint diseases?
osteoarthritis
What is osteoarthritis?
progressive, irreversible loss of joint cartilage
Most commonly affected joints by osteoarthritis?
cervical and lumbosacral spine, hip, knee, 1st MTP joint, hands (DIP, PIP, 1st CMC joint)
Risk factors for osteoarthritis
joint vulnerability (systemic factors, intrinsic joint factors) and joint loading
Systemic risk factors for OA
increased age, female gender, racial/ethnic factors, genetics, nutrition
Intrinsic joint risk factors for OA
previous damage, muscle weakness, increasing bone density, malalignment, proprioceptive deficiencies
Does OA impact extra-articular organs?
No
Does OA impact men or women more?
women
Presentation of OA
pain (bone pain, aching to severe, localized to radiating, affects sleeping), stiffness lasting <30 minutes (worse with inactivity), swelling, joint instability, decreased ROM, locking and grinding
PE OA
TTP, joint effusion, possible deformity, crepitus, antalgic gait, decreased ROM, muscle atrophy
What are OA deformities you can see in the knees?
genu varum, genu valgum
what are OA deformities you can see in teh hands?
Heberden nodes (DIP) and Bouchard nodes (PIP)
Films for OA
Plain films (joint space narrowing, osteophytes, subchondral bone sclerosis/cysts), MRI (r/o if needed), US (not routinely used)
What labs are used for OA?
nothing specific, just r/o other causes
Treatment for OA?
RICE, unloader brace, injections, NSAIDS/tramadol/glcuosamine and chondroitin sulfate, physical therapy/aquatic therapy, patient education, CAM
Surgical options for OA?
arthroscopy is NOT indicated for OA, joint replacement
What’s the most common form of autoimmune arthritis?
Rheumatoid arthritis
What types of joints does RA typically impact?
synovial joints
What’s the cause of RA?
unknown triggers for immune response in synovial tissue
Which genetic marker determines both risk and severity of RA?
HLA-DR4
What are possible triggers of RA?
bacterial antigens (mycobacteria, strep, mycoplasma, e. coli, h. pylori), viral agents (EBV, rubella, parvovirus), smoking, hormonal changes