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MRCP 1 > Neuro > Flashcards

Neuro Flashcards

1
Q

Failure of vertical gaze lesion location?

A

Dorsal midbrain

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2
Q

Secondary prevention for future strokes?

A

Clopidogrel

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3
Q

String of pearls/beaded appearance of carotid or renal artery?

A

Fibromuscular dysplasia

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4
Q

Ropinirole class?

A

Dopamine agonist

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5
Q

First line for relapsing remitting MS?

A

B-interferon

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6
Q

AED with no warfarin interaction?

A

Lamotrigine

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7
Q

Most common cancer assoc with LEMS?

A

Small cell lung

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8
Q

Weakness and dry mouth, absent tendon reflexes?

A

Think LEMS

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9
Q

Crossed neurological signs - think?

A

Brainstem lesion/involvement

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10
Q

Classical MRI sig in vCJD?

A

Pulvinar sign of the thalamus

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11
Q

Lateral medullary syndrome arteries?

A

Vertebral
PICA

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12
Q

Negative prognostic factors in GBS?

A

Age >40
Rapid onset
Confirmed bacterial illness - especially campylobacter
High GM1
Ventillation

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13
Q

CCB used in SAH?

A

Nimodipine

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14
Q

Tinnitus (unilateral), lack of corneal reflex?

A

Vestibular schwannoma

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15
Q

Combination of 3rd, 4th, 1st and 2nd branches of 5th, and 6th nerve palsy?

A

Cavernous sinus lesion

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16
Q

Mention of a ‘shawl-like or cape’ distribution?

A

Syringomyelia

17
Q

First line for occular pyridostigmine? Starting dose?

A

Pyridostigmine
30mg QDS

18
Q

Global wasting of the hand muscles? Lesion where?

A

T1

19
Q

Jerk/oscillating nystagmus lesion location?

A

Cerebellum

20
Q

Meningitis prophylaxsis for contacts?

A

Rifampicin or cipro

21
Q

GN in SLE?

A

Diffuse proliferative

22
Q

First line to prevent angina?

A

CCB / BB

23
Q

First line for migraine (if not super frequent)

A

Paracetamol with metaclopramide

Then naproxen

Then triptan

24
Q

Most common visual field defect in IIH?

A

Enlarged blind spot(s)

25
Q

Cluster headache prevention?

A

Verapamil

26
Q

Largely the first line AED?

A

Lamotrigine

27
Q

Good AED in liver impairment?

A

Topiramate

28
Q

Topiramate SEs?

A

Renal stones
Loss of appetite and weight loss
Peripheral paralysis

29
Q

Contralateral weakness, arm/face more than leg and aphasia, might have dyspraxia, homonymous hemianopia?

A

MCA

30
Q

Contralateral weakness, leg more than arm. Might be confused, mute, apathetic?

A

ACA

31
Q

Cortical blindness, CN3, memory loss, hemiballismus?

A

PCA

32
Q

Parkinsonian with pronounced postural instability?

A

Think PSP

33
Q

What is the protein abnormality in AD, PSP and FTD?

A

Tau

34
Q

What do tau inclusions stain with?

A

Ubiquitin - TDP43

35
Q

Parkinsonism, automonic, cerebellar, pyrimadial/extrapyramidal features?

A

MSA?

36
Q

What is the protein in MSA?

A

Alpha-synuclein

37
Q

Myotonic dystrophy type 1 vs 2?

A

Type 1 - ptosis, facial weakness/wasting, hand myotonia

Type 2 - PROXIMAL MD - primarily proximal lower limb weakness and myotonia

38
Q

Progressive ataxic syndrome with marked dorsal column involvement, pes cavus, cardiomyopathy?
How is it inherited?

A

Friedrich’s ataxia

AR

39
Q

CADASIL gene?

A

NOTCH3

MRCP 1 (24 decks)

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