Immunology

Question 1

Which cytokine does tacrolimus inhibit?

Answer 1

IL-2

Question 2

Urinary free light chains?

Answer 2

Myeloma

Question 3

Sounds like nephrotic syn but mention of low total cholesterol?

Answer 3

Protein losing enteropathy

Question 4

Ig def in some anaphylaxsis cases?

Answer 4

IgA

Question 5

Di George?

Answer 5

CATCH 22

Cardiac abnormalities
Abnormal facies
Thymic hypoplasia
Cleft palette
Hypocalcaemia
Chromosome 22 deletion

Question 6

Only antibody able to cross the palcenta?

Answer 6

IgG

Question 7

Inheritance of most complement deficiences?

Answer 7

AR

Question 8

SLE complement def association?

Answer 8

C1q

Question 9

Antibodies in APLS?

Answer 9

Anto-cardiolipin
Anti-B2 microglobulin
Lupus anticoagulant

Question 10

Culprits in latex-fruit allergy syndrome?

Answer 10

Bananas
Kiwi
Chestnut
Avocado

Question 11

Latex sensitivity reaction type?

Answer 11

Type IV

Question 12

Latex anaphylaxis reaction type?

Answer 12

Type I

Question 13

Two linked Ig def in URTI?

Answer 13

IgA with IgG2

Question 14

“Anaphylaxis” after fish but negative tryptase?

Answer 14

Scromboid poisoning

Question 15

GN with “pauci-immune” appearance on biopsy?

Answer 15

GPA

Question 16

ALternative pathway complement deficiency (C5-C9) susceptible infection?

Answer 16

Neisseria

Question 17

Which complement level in low in hered angio even between attacks?

Answer 17

C4

Question 18

What other than TB can BCG be used for

Answer 18

In situ bladder Ca

Question 19

What cell is abnormal in CLL?

Answer 19

B lymphocyte

Question 20

Mixed cryoglobulinaemia?

Answer 20

Hep C

Question 21

What is unusual about IgA and the complement pathway?

Answer 21

It does not activate it in the normal way but instead by the alternative one