Neuro 1 Flashcards
Stroke involving right anterior cerebral artery would have the most significant effect on which part of the body?
Left leg
Brain supplies body in contralateral manner
ACA supplies legs - because medial portion of hemispheres hence why it’s left leg
Obstruction of arachnoid granulations prevents CSF being reabsorbed into dural venous sinuses. This associated with?
Meningitis
Can cause inflammation, which is what prevents fluid being reabsorbed into dural venous sinuses
35 Y/O man visits his physician because experiencing sporadic, involuntary movements and was becoming increasingly uncoordinated. Got Huntington’s disease - AD disease caused by loss GABAergic neurones in basal ganglia - which structure is affected?
Caudate nucleus/ putamen
affected because MRI can see caudate nucleus is degenerated
Young woman pushed cotton bud into ear too far
Can see perforated tympanic membrane - which nerve is most likely to be damaged
Nerve to stapedius because nerve which connected to facial nerve and stapedius is one of the bones involved in connecting eardrum to hearing parts of ear
What is CN1 and what does it do?
Olfactory nerve
Mainly involved in transmitting info relating to smell
Where is the olfactory tract and olfactory bulb located?
Proximally have olfactory bulb
Distally (Closer to cerebral hemispheres) have olfactory tract
What structure does the olfactory bulb go through?
Fasicles of olfactory nerve pass through the cribiform plate from muscosa of upper nasal cavity, join to olfactory bulb + go down through the tracts
How many pairs of cranial nerves are there?
Left and right cranial nerves
eg. Left and right olfactory bulbs
Where is the gyrus rectus in relation to the olfactory tracts?
Olfactory tract is on top of gyrus rectus
What is lateral to the gyrus rectus and the olfactory tract?
Olfactory sulcus
What is the olfactory trigone?
Where the olfactory tract divides into the medial and lateral olfactory stria
What is posterior to the olfactory trigone?
Anterior perforated area which give blood supply to deep grey matter nuceli mostly from branches of MCA + close to limbic lobe
What is CNII and what does it do?
Optic nerve + transmits visual sensory information
What are the 3 parts of the optic nerve?
- optic nerve
- optic chiasm
- optic tract
Where does the optic nerve go?
Straight to the eye
What is the optic chiasm?
Joint structure where L+R optic nerve meet
Where is the optic tract and where does it go?
Behind the chiasm and divide into optic radiations
go posteriorly into occipital lobe to primary visual cortex area
Where is the primary visual cortex area?
Calcarine sulcus in occipital lobe
How does the optic nerve enter skull to the brainstem?
Via the optic canal in the sphenoid bone
What travels with the optic nerve through the optic canal?
Ophthalmic artery - branch of internal carotid artery
What structure is related close to the optic tract and what way?
Cerebral peduncles
optic tract curves around cerebral peduncles (pillar like structures in midbrain)
What does the optic chiasm sit on top of?
Pituitary gland
What is the clinical significance of the optic chiasm sitting on top of the pituitary gland?
Inflammation or outgrowth of pituitary gland can cause compression optic nerves
= bilateral hemianopoeia
What are the 2 optic radiations?
Meyer’s loop = lower optic radiation
Balm’s loop = upper optic radiation
Where do the optic radiations terminate?
visual cortex (calcarine sulcus)
What is the brainstem made up of?
Midbrain superiorly
Pons - middle
Medulla - inferiorly
What are the two junctions in the brainstem?
Ponto-mesencephalic junction (Superiorly)
Ponto-medullary junction
(inferiorly)
From which junction does many CN emerge?
Pontomedullary junction
What is the crus cerebri?
On the cerebral peduncles transmits corticospinal tract (motor tracts)
What are the mammillary bodies?
2 small pea structures on side of the cerebral peduncles - underneath the optic chiasm
What do the cerebral peduncles hold?
Cerebral hemispheres
Where is the interpeduncular fossa and what CN originates in this structure?
In between the cerebral peducnles and CN3 originates from it
What is the basilar pons?
Where basilar artery runs on top of
What are the middle cerebellar peduncles?
Bumps on the lateral side of the pons
From the tracts through which the cerebellum receives and give out information
Attaches cerebllum to the brainstem
How many cerebellar peduncles are there?
3:
superior - seen in posterior aspect - attaches cerebellum to brainstem
middle
inferior - small bump just below middle cerebellar peduncle (medial to middle)
What is the ventral medial fissure?
Line in between the 2 aspects of the medulla
What is lateral to ventral medial fissure?
Pyramids of medulla - where corticospinal tract criss cross .˙. known as pyramidal tract
What are the olives?
Lateral to the pyramid - small bead like structures on the side
Which clinically important tract descends into the pyramids of the medulla?
Corticospinal tract (pyramidal)
Why might damage to inferior cerebella peduncle cause gait ataxia?
Major route for sensory information (unconscious proprioception) about lower limbs to reach cerebellum; without it walking becomes disordered and uncoordinated.
What is the midbrain made up of?
Tectum (roof) + tegmentum (more anteriorly)
What structure is between the tectum + tegmentum?
Cerebellar aqueduct in midline
What is more prominent from the lateral aspect - the medial cerebellar peduncle or the cerebral peduncle?
Medial cerebellar peduncle
What is visible on the posterior view of the brainstem?
The 4th ventricle (if the cerebellum is removed)
How is the 4th ventricle connected to the third ventricle?
By the cerebellar aqueduct - runs vertically in the brainstem
What is the function of the superior and inferior colliculus?
Transmit sensory information
Can see midbrain on posterior aspect
What is the cruciform sulcus?
Cross like structure in between superior and inferior colliculus
Where is the frenulum?
Inferior to the inferior colliculus
What are visible superiorly on the posterior aspect of the brainstem?
The ends of the thalamus - pulvinar nuclei
What is the rhomboid fossa and what is it bounded by?
Rhomboid shaped depression
upper 2/3 = pons
lower 1/3 = medulla
What is the medulla like?
Largely closed
Superiorly opens up to become the open medulla
continues down to join the spinal cord
What is the obex?
Site for the emetic centre or the chemoreceptor trigger zone (CTZ).
No Blood brain barrier so helps sample blood
If any emetic material - can test and cause emesis
What is the alar plate of the neural tube and its function?
Sensory + towards the back
What is the basal plate of the neural tube and its function?
Anterior - motor plate
Where is the sulcus limitans in the neural tube?
between alar and basal plate
How does this change in a fully developed human?
The brainstem opens up
opens up at the medulla just after the obex
Alar plates end up laterally located
Basal plates in medial aspect