Abdomen V Flashcards
What are suprarenal glands?
Endocrine glands - produce hormones
Where do the suprarenal glands lie?
Between sup pole kidney and diaphragm
Describe the differences in shape of the right and left gland
Right - pyramidal
Left - semilunar
What is the significance of the renal fascia surrounding the suprarenal glands?
Separates the glands from the kidneys, if kidneys are disturbed suprarenal gland is protected
What are the 2 parts of the suprarenal glands?
Cortex (outer) - yellow
derived from mesoderm and secretes corticosteroids and androgens
Medulla (inner) - brown
derived from neural crest
main source catecholamines - adrenaline and noradrenaline
Which 3 arteries supply the suprarenal glands?
Superior suprarenal arteries - off inferior phrenic (off aorta)
Middle suprarenal artery - off abdominal aorta
Inferior suprarenal artery - off renal artery
Why do the suprarenal glands have such a good blood supply?
As produce hormones need to go into blood
What is the venous drainage of the suprarenal glands?
Via left and right renal suprarenal veins
Left -> left renal veins
as aorta in way, safer to join renal vein instead of going over
Right -> IVC directly
What are the functions of the kidney?
Excretes most waste products of metabolism
Acts as sieve to filter blood
Controls water and electrolyte balance of body
Maintains acid-base balance body
Secretes hormones and renin into blood stream
How much blood does the kidney filter?
113-144 pints blood/hour
Blood flow to kidney is higher than to heart
Blood filtered 400x/day
Where are the waste products of metabolism from urine stored?
Stored in the bladder and expelled from body via urethra
What are the different functioning parts of the kidney?
Including medulla and cortex
What is the location of the kidneys?
Primary retroperitoneal organs Located at level of T12 - L3 Ribs 11+12 left Ribs 12 right Hila kidney - L1 Closely related to diaphragm and move with it on inspiration
Why is the right kidney slightly inferior to the left kidney?
A liver is on the RHS
What are the anterior relations of the left and right kidney?
Right - hepator-enal pouch + greater sac
fluid can build here
Liver
Left - stomach bed (lesser sac)
What are the posterior relations of the kidney?
Closely related to 11th and 12th rib
Muscles of the posterior abdominal wall
Medially have psoas minor if present + psoas major
Laterally have quadratus laborum
Lateral edge have transversus abdominis
Superior ribs are related to the diaphragm
What is the function of the renal coverings?
Fascial layers that
support the kidney
hold the kidneys in position against the posterior abd wall
What are the layers of the renal coverings?
- Renal capsule - closely adherent to surface
- Perinephric fat - w/in perineal space
- Renal fascia - condensation areolar connective tissue
Continuous with transversalis fascia and fascia over diaphragm - Paranephric fat - external to capsule (lots of it hence removed in donors)
What is the hilum of the kidney?
Entrance point of structures in the kidney
Vein, artery, ureter (anterior to posterior)
+ lymph vessels + sympathetic fibres
What does the renal cortex extend into?
Outer layer of kidney = renal cortex
Renal cortex extends into renal columns
Where are the renal columns located?
Renal columns located laterally to renal pyramids - extensions of cortex
Describe the renal pyramids
Each pyramid has a base - closely related to the cortex
Contains loops of nephrons and collecting ducts
Apex - tip of pyramid and runs into minor callices through papilla
Papilla is at the tip of the triangle opening into minor calyx
What is the renal space filled with?
Filled with perinephric fat
What structure does the minor callices come to form?
Come together as major calyx
What do the major callices come to form?
Form renal pelvis = Dilated superior portion ureter
What is the renal sinus?
Contains renal pelvis
Upper extended part of urethra
Perinephric fat continued into hilum, sinus and surrounds all structures
What happens to the renal artery after it enters the kidney?
Splits into 5 segmental arteries
4 anterior segmental arteries
1 posterior segmental artery
Segmental arteries give rise to lobar arteries
Interlobar arteries - run towards cortex
Arcuate arteries - arch over base pyramid
Interlobular arteries
Give off afferent glomerular arterioles - Bowman’s capsule
What are the segments of the kidney supplied by the different segmental arteries?
- Apical
- Caudal
- Anterior superior
- Anterior inferior
- Posterior
What is a lobe of the kidney?
Made of renal pyramid and corresponding superior cortex
Describe the venous drainage of the kidney
Follow arteries
Efferent glomerular venules drain interlobular veins -> arcuate -> interlobar veins -> multiple renal veins
Renal veins contribute to formation of L+R renal vein - don’t necessarily align to segmental arteries
Where does the right renal vein pass?
Passes posterior to the second part of duodenum and head of pancreas
All vessels of RHS go straight to IVC
What are the discrepancies of the left and right renal veins?
Left enters the iVC superior to the right renal vein
Left is 3x larger than the right renal veins
Left may be compressed by aortic/sup. mesenteric aneurysms as closely related
Receives left gonadal vein, inferior phrenic and suprarenal vein
What is nephroptosis?
Dropped kidney
Layers of renal fascia don’t fuse firmly inferiorly
hence, abnormally mobile kidneys may descend >3cm when body is erect
Suprarenal glands stay in place as lie in separate fascial compartment and more firmly attached to diaphragm
Symptoms intermittent pain in renal region
Relieved by lying down - appears to result from traction on renal vessels
List some congenital abnormalities?
Bifid renal pelvis and ureter (fairly common) - results from division ureteric bud - primordial renal pelvis + ureter
May be unilateral/bilateral - separate openings into bladder are uncommon
Horseshoe kidney -
when kidneys first formed, kidneys are close together in pelvis, 1/6000 fetuses inf. pole kidney fuse to form horseshoe
Describe the lymphatic drainage of the kidneys
Follow the renal veins
Drain into L+R lumbar nodes (caval + aortic)
near origin of renal artery
Where do the sympathetic nerves
arise and what is their function?
T10 - L2
Post ganglionic sympathetic from renal plexus - which follows renal arteries
Fn = vasomotor regulating blood flow and renin secretion
Is there PS nerve supply to the kidneys?
No evidence of PS supply
Some say from vagus nerve
Is renal function dependent on innervation?
Not dependent on innervation as regulated by hormones
Displayed by kidney transplants, kidneys still work despite nervous innervation being severed
What is staghorn canaliculi?
Build up of struvite - solid mass takes formation kidney itself
Caused by recurrent UTI that increase ammonia production, increase pH and decrease phosphate solubility
What is a ureter and its function?
Long, muscular tube
20-30cm
3mm diameter
Transports urine from kidney to urinary bladder (pelvis)
Begin as continuation renal pelvis - susceptible to damage as travel long way
Are the ureters intra or retroperitoneal?
Retroperitoneal lined w/ stratified transitional epithelium
What is the course of the ureters in the abdomen?
- Descends anterior to psoas major muscle - opposite tips lumbar transverse process
- Crosses anterior to genitofemoral nerve - nerve runs anterior to psoas major
- Obliquely crossed by gonadal vessels - as travel from abdominal aorta to pelvis
- Enters pelvis anterior to bifurcation common iliac artery to enter pelvis - L4/5
Describe the course of the ureter through the pelvis?
- Runs downward in front, on internal iliac artery to reach ischial spine
- Turns medially opposite ischial spine and forward to enter base bladder (upper lateral angle)
- Near termination (before enters bladder) crossed by:
- vas deferens
- uterine artery - water under the bridge, ureter lies underneath artery - Passes obliquely through wall bladder for 3/4 inch before opening into bladder cavity
What is the importance of the ureters entering the bladder at an angle?
Helps prevent back-flow urine
What bony structures can be used to trace the ureters?
On film sacroiliac joint and ischial spine help to trace the course of the ureter
What are the 3 points of constriction on the ureters and their significance?
- Ureteropelvic junction - connection between renal pelvis and ureter
- Crossing ureter over external iliac/ common iliac artery
- Ureterovesical junction - site of entrance into bladder
Stones can get stuck at these points
What are kidney stones?
Common clinical solid mass
Formed in kidney - may pass into ureter and impinge flow urine ->complete intermittent
What is the passage of kidney stones?
kidney -> renal pelvis -> ureter
Can cause excessive distension muscular tube
What is a ureteric calculus?
Causes sever pain (ureteric colic)
As it’s gradually forced down ureter by waves contraction to overcome obstruction
Pain referred from loin -> groin
Also lumbar region, hypogastric region, external genetalia, testes
Referred cutaneous areas that are also innervated by spinal cord segments and sensory ganglia, also supply ureter (T11-T12)
What is the arterial supply of the ureter?
Pick up branches from (sup to inf)
- renal artery
- gonadal artery
- common iliac artery
- internal iliac artery
What is the venous drainage of the ureters?
Occurs in corresponding veins to arteries
Where does the bladder originate?
Endodermal origin and develops from urogenital sinus
What is the bladder?
Distensible hollow organ capable holding 1L urine
Size, shape, position and relations vary according to content + content surrounding organs
What is the shape of the bladder?
3 Sided pyramid - apex points toward pubic symphysis
What does the apex of the bladder give rise to?
Median umbilical ligament
Runs towards umbilicus = remnant urachus - fibrous remnant of allantois
Fn - drain foetal urinary bladder
What is the direction of the base of the bladder?
Faces postero-inferiorly .˙. bladder has 2 inferolateral surfaces
What structure does the neck of the bladder surround?
Surrounds the urethra - fixed in position
What are the structures surrounding the bladder?
Bladder is on inside the anterior abdominal wall
At back can see seminal vesicles
Under bladder have prostrate
What is the function of the fibromuscular bands?
Ligaments hold the bladder neck in place
Sits above the pelvic fold
Neck supported by endopelvic fascia + levator ani muscle
Important as allows for continence
What is the pubovesical ligament?
Holds bladder in place in females
Wraps around neck + urethra - attaches it to pubic symphysis
How is stress incontinence after parturition caused?
May cause ligaments and pelvic floor to be weakened .˙. neck prolapses below floor
Occurs when intra-abdominal pressure is increased eg. coughing, sneezing
What is the puboprostatic ligament?
Wraps around prostate and attached to pubic symphysis
Neck surrounded by internal urethral sphincter (smooth muscle)
What muscle forms the walls of the bladder?
Detrusor muscles
What is the inner surface of the bladder lined by?
Transitional epithelium
Where are the attachments of the vesical mucosa?
Attached loosely to detrusor muscle
Except at trigone region
Describe the mucosa when the bladder is full and empty
Full - mucosa stretched out
Empty - mucosal folds
Describe the detrusor muscle and how it works to expel urine
Muscular layer urinary bladder - trabeculated appearance
When bladder stretched PS nervous stimulation occurs - causes contraction detrusor muscle
Causes bladder to expel urine through urethra