NEUR 0010 - Chapter 14 Flashcards

1
Q

What are the high, middle, and low levels of motor control?

A

Strategy, tactics, and execution

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2
Q

What are the structures associated with each level of the motor control hierarchy?

A

High = strategy (association areas of neocortex, basal ganglia), middle = tactics (motor cortex, cerebellum), low = execution (brain stem, spinal cord)

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3
Q

What are the lateral pathways for?

A

Voluntary control of distal musculature; under direct cortical control

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4
Q

What are the ventromedial pathways for?

A

Control of posture and locomotion, under brain stem control

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5
Q

What brain areas control the lateral vs ventromedial pathways?

A

Cortex vs brainstem

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6
Q

What is the most important component of the lateral tract?

A

Corticospinal tract

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7
Q

Where do the axons of the CS tract originate?

A

Mostly in the motor cortex, some in the SS areas of the parietal lobe

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8
Q

Where do the axons of the CS tract go?

A

Start in the motor cortex or SS area of parietal lobe; pass through internal capsule between telencephalon and thalamus; through cerebral peduncles in the midbrain; through the pons; tract at the base of the medulla in the medullary pyramid

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9
Q

What happens to the CS tract after it becomes the medullary pyramids?

A

Decussates and continues down to the spinal cord’s lateral column

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10
Q

When does the CS tract decussate?

A

After becoming the medullary pyramids, right before it continues onto the lateral column of the spinal cord

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11
Q

Where do the CS tract axons terminate?

A

In the dorsolateral region of the ventral horns and intermediate gray matter (same location as motor neurons/interneurons that control distal muscles, esp. flexors)

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12
Q

What is the rubrospinal tract?

A

a smaller component of the lateral pathways

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13
Q

Where does the rubrospinal tract originate?

A

The red nucleus in the midbrain’s tegmentum

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14
Q

Where do the axons in the rubrospinal tract go?

A

Start in the red nucleus of the midbrain; decussate in the pons; join corticospinal tract in the lateral column of the spinal cord

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15
Q

What is the main source of input to the rubrospinal tract?

A

Frontal cortex that contributes to the corticospinal tract

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16
Q

What happens after lesions in the lateral pathways?

A

No fractionated movements of arms/hands; slower movement, less accuracy; functions can gradually recover if only damage to CS tract, but no recovery if damage to both CS and RS tracts; contralateral paralysis if damage to the motor cortex or CS tract

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17
Q

What are the four descending tracts of the VM pathways?

A

Vestibulospinal, tectospinal, pontine reticulospinal, medullary reticulospinal

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18
Q

What does the VM pathway do?

A

Uses sensory info about balance/body position/visual environment to maintain balance and posture

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19
Q

What do the vestibulospinal and tectospinal tracts do?

A

Keep head balanced, turn head to stimuli

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20
Q

Where do the vestibulospinal tracts originate and go?

A

Start in vestibular nuclei of the inner ear (input from vestibular labyrinth of the inner ear); go bilaterally down spinal cord and activate cervical spinal circuits to guide head movement

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21
Q

Where does the tectospinal tract originate and go?

A

Starts in superior colliculus of midbrain (input from retina, V1, SS, audition, etc.); maps the world around us and causes the head to focus on a new stimulus

22
Q

What do the pontine and medullary reticulospinal tracts arise from?

A

The reticular formation of the brain stem: just under the cerebral aqueduct and fourth ventricle

23
Q

What does the pontine reticulospinal tract do?

A

Enhances antigravity reflexes of the spinal cord; facilitates lower limb extensors; maintain standing posture

24
Q

What does the medullary reticulospinal tract do?

A

Liberates antigravity reflexes of the spinal cord from reflex control; allows a fine balance of posture vs not

25
Where are Areas 4 and 6?
4 is anterior to the central sulcus, on precentral gyrus; 6 is just anterior to Area 4
26
What is primary motor cortex M1?
Area 4
27
What two components make up Area 6, and what do they do?
PMA and SMA: premotor area and supplementary motor area; specialized for skilled voluntary movement
28
How do the processes of PMA and SMA differ?
SMA sends axons to distal motor units directly; PMA connects with reticulospinal neurons to innervate proximal motor units
29
Which activates distal vs proximal, PMA or SMA?
SMA is distal, PMA is proximal
30
What kind of signals/messages/functions does Area 6 carry out? Why?
What actions to convert into signals, and how to do so; because it receives information from the prefrontal and parietal lobes
31
When you're instructed to only think about performing a practiced movement, what areas are active?
Area 6, but not area 4
32
What is the ready/set/go of the prefrontal/parietal/area 6?
Ready is the parietal and frontal lobes and attention centers; Set is the SMA and PMA strategizing; Go is the performance after the trigger stimulus
33
Where are the basal ganglia?
In the telencephalon
34
What is the major subcortical input to Area 6?
From the VLo nucleus (ventral lateral nucleus)
35
Where does input to the VLo come from?
Basal ganglia
36
What are the four components of the basal ganglia?
Caudate nucleus, putamen, globus pallidus, subthalamic nucleus
37
What is the striatum?
The combination of the putamen and globus pallidus
38
What structure is the source of output to the thalamus?
Globus pallidus
39
What is the direct path from cortex back to cortex by way of the SMA?
Cortex to striatum to globus pallidus to VLo to SMA in the cortex again
40
What is the direct motor loop?
Cortex synapses (E) with putamen, which synapses (I) with globus pallidues, which synapses (I) with VLo, which synapses with cortex (E) and discharges movement-related SMA cells
41
What is Parkinson's disease?
Hypokinesia: too much inhibition by basal ganglia of thalamus; helped by administering dopamine
42
What is Huntington's disease?
Hyperkinesia: too little inhibition by basal ganglia of thalamus; characterized by chorea/ballism
43
What layer of motor cortex activates motor neurons?
Layer V
44
Where does layer V of the motor cortex receive input from?
Other cortical areas (area 6) and the thalamus (VLc)
45
What does VLc do?
In the thalamus: relays info from the cerebellum
46
How does M1 command voluntary movement?
Employs most of itself as active, and each cell represents a "vote" that gets tallied and averaged to determine the direction of motion by vectors
47
What is the cerebellum for?
Controlling the finely-tuned sequence of events that occur during movement
48
What does the vermis do?
Sends output to brainstem structures that contribute to VM descending spinal pathways to control axial musculature
49
What do the cerebellar hemispheres do?
Related to brain structures that contribute to lateral pathways, esp. cortex
50
What is the motor loop through the lateral cerebellum?
Layer V, areas 4/6, SS areas, posterior parietal areas project to pontine nuclei; project to cerebellum; project back to motor cortex through thalamic VLc
51
What is the purpose of the motor loop through the lateral cerebellum?
Planned, voluntary, multi-joint movements; compared intentions with outcomes