Nervous Tissue Flashcards
Neuron
Basic functional unit that receives and transmits nerve impulses; consists of:
-Cell body
-Dendrites
-Axon
Cell body
Contains:
-large nucleus surrounded by abundant RER with Nissl bodies
-dendrite processes from soma (site for synapses)
-axon to transmit signals to neurons or cells of effector organs. Originates from soma at axon hillock and ends in terminal arborization to form synapses
Lipofuscin
Fine yellow-brown pigment granules composed of residues of lysosomal digestion that accumulates in cytoplasm; considered an aging/wear and tear pigment
Neuroglia
Protect neurons and support neuronal survival and activities; participate in regulation of neuronal propagation of impulses
Gap junctions occur between neuroglial cells
4 kinds of CNS glial cells
Oligodendrocytes
Astrocytes
Microglia
Ependymal cells
2 kinds of PNS glial cells
Neurolemmocytes (Schwann cells)
Satellite cells
Oligodendrocytes
Produce and maintain myelin for myelinated axons
Smaller somas than astrocytes
Multiple processes that produce myelin
Astrocytes
Provide structural and metabolic support to neurons
Remove ions and NT’s that have been released in extracellular space
Release glucose for neuronal energy metabolism
Help maintain BBB (blood-brain barrier) - continuous layer over CNS capillaries
Form cellular scar tissue (glial scar) for damaged areas
Microglia
Small cells with short, irregular processes
Phagocytic - remove debris, viruses, and other microorganisms
Ependymal cells
Columnar to cuboidal cells lining ventricles of brain and central canal of spinal cord
Selective barrier between brain parenchyma and CSF
Ciliated in some areas to facilitate movement of CSF
Neurolemmocytes (Schwann cells)
Produce myelin sheaths outside of CNS
Plasma membrane of neurolemmocyte wraps around segment of axons many times - myelinated axons
Gap between adjacent neurolemmocytes is called Node of Ranvier
Satellite cell
Collections of neuronal cell bodies outside of CNS
Found in ganglia
Small support cells that form a layer over surface of neuronal cell bodies
Provide trophic support for neurons and regulate their microenvironment
White matter
Main component is myelin from myelinated axons
Few neuronal cell bodies in - astrocytes and microglia are present
Gray matter
Consists of abundant neuronal cell bodies and dendrites
Where most of synapses occur
Astrocytes and microglia are present
Meninges
Specialized membranes that provide protection, physical stability, and shock absorption for CNS
-Dura mater
-Arachnoid
-Pia mater