Muscle Flashcards
Skeletal muscle
Single, very long, cylindrical, multinucleate cells with obvious striations. Nuclei run parallel along the edge of fibers
Pink or red due to presence of rich blood supply and myoglobin (oxygen transport)
Limited regeneration via satellite cells
Collagenous CT around skeletal muscle
Epimysium - surrounds entire muscle
Perimysium - surrounds bundles of muscle fibers (fascicles)
Reticular CT around skeletal muscle
Endomysium - surrounds each muscle cell and includes a basal lamina
Sarcomeres
Functional unit of myofibril (muscle cells)
Organized arrangement of protein molecules produces striped appearance
During contraction, I band and H zone become narrower. A band does not change in length
Components of sarcomeres
A band - dark; thick filaments (myosin) and overlapping thin filaments (actin)
I band - light, thin filament region
Z disk - attachment point for thin filaments and extend towards the center of the sarcomere (named for its zig-zag shape)
H zone - central part of sarcomere without thin filaments
M line - binds the thick filaments
Myosin
Thick filaments that binds with actin to contract muscle
Actin
Thin filaments that when bound by myosin, stimulates contraction in muscles
Golgi tendon organs
Located at junction of a muscle and its associated tendon
monitor the force of muscle contraction
Inhibitory feedback is provided to the muscle to cause relaxation of the contracting muscle
Cardiac muscle
Branching chains of cells; uni- or binucleate; striations
Have intercalated disks - specialized collections of end-to-end junctions
Extensively supplied with capillaries
Limited regeneration
Difference between T tubules in cardiac muscle and skeletal muscle
In cardiac muscles, T tubules are not as regularly arranged. Form diads with one terminal cistern and one T tubule. Larger and more numerous with less abundant sarcoplasmic reticulum. More mitochondria
In skeletal muscles, T tubules form triads with two terminal cisternae and one T tubule
Smooth muscle
Single cells, fusiform, uninucleate, no striations
Nuclei are twisted in shape due to twisting when contraction occurs
No T tubules present
Has good self regeneration due to dividing muscle cells