Nervous System/Nerve cells Flashcards
What makes up the Central Nervous System (CNS) ?
Brain and spinal cord
The Peripheral Nervous System is made up of all tissue outside of the CNS, What are the three main PNS?
Stomatic Nervous System
Autonomic Nervous System
Enteric Nervous System
What are the sensory and motor functions of the Stomatic Nervous System?
Sensory: Special sense receptors transmit info to CNS
Motor: Transmits info from CNS to skeletal muscles
What are the sensory and motor functions of the Autonomic Nervous System?
Sensory: Receptors in visceral organs transmit info to CNS
Motor: Transmits info from CNS to Cardiac and smooth muscle glands
What are the sensory and motor functions of the Enteric Nervous System?
Sensory: Monitor chemical changes and stretch in GI tract
Motor: Innervates smooth muscle, glands, and endocrine cells in GI tract
What are the two divisions in the Autonomic Nervous System that deal with flight or flight and rest and digest activities?
Sympathetic Division - Fight or Flight
Parasympathetic Division - Rest and Digest
What are the 4 types of Neuroglia? (structures that hold the nerves together)
Astrocytes
Oligodendrocytes
Microglia
Ependyma Cells
In the Peripheral Nervous System what is the difference between Schwann Cells and Satellite Cells?
Schwann Cell (PNS) - forms and maintains myelin sheath and involved in axon regeneration
Satellite Cells (PNS) - structural support and exchange of materials between interstitial fluid
What two factors are necessary for the production of a nerve impulse
- The existence of a resting membrane potential
- The presence of a specific type of ion channel
Explain the processes of an action potential and the corresponding ion movements/ion channel states
- Resting Membrane Potential - Voltage-gated Na+ and K+ channels closed. Little movement of ions.
- Depolarisation - Voltage-gated Na+ channel opens. Na+ moves into the cell
- Repolarisation - Voltage-gated Na+ channel inactivated. Voltage-gated K+ channel opens. K+ moves out of cell
- Hyperpolarisation - Voltage-gated Na+ channel closed. Voltage-gated K+ channel open. K+ continues to exit cell
- Resting Membrane Potential - Voltage-gated Na+ and K+ channels closed. Na+/K+ pumps restore resting potential
Explain Absolute Refractory Period and the Relative Refractory Period
A = Absolute Refractory Period - second action potential cannot be generated
B = Relative Refractory Period - second action potential can be generated
What is the main difference between Continuous Propagation/Conduction and Saltatory Propagation?
Saltatory Propagation only occurs in nerve cells insulated with myelinated axons, allows the skipping of repolaristation and leaping of action potential between the Nodes of Ranvier
In relation to signal transmission between synapses what ends are the Pre Synaptic cell and the Post Synaptic Cell?
Pre synaptic (neuron) cell - cell sending the signal
Post synaptic (neuron cell - cell receiving the signal
What is the main feature of a Electrical synapse?
Both the Pre Synaptic and Post Synaptic cells have aligning channels forming a “Gap Junction”
Explain the six steps involved in Chemical Synapse action potential transmission
- Action potential moves down axon terminal
- Voltage gated Ca2+ channels open
- Ca2+ enters the cell
- The influx of Ca2+ in the cell then signals the vesicles containing neurotransmitters
- Vesicles then move to plasma membrane
- Docked vesicles then release neurotransmitter by exocytosis into the synaptic cleft
- Neurotransmitter diffuses across the synaptic cleft and binds to post synaptic receptors
What is the space between the Presynaptic Cell and Postsynaptic in Chemical Synapse action potential transmission?
Synaptic Cleft
In relation to Post Synaptic Potentials explain Excitatory postsynaptic potential and Inhibitory postsynaptic potential
- (EPSP’s) Excitatory postsynaptic potential - depolarising postsynaptic potential brings postsynaptic membrane closer to threshold
OR
2. (IPSP's) Inhibitory postsynaptic potential - hyperpolarising postsynaptic potential takes the postsynaptic membrane closer from threshold