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Pre Reg > nervous system > Flashcards

nervous system Flashcards

1
Q

clozapine se

A

neutropenia

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2
Q

clozapine tests

A

leucocyte and different blood counts

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3
Q

quetiapine and amiodarone causes what…

A

qt prolongation

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4
Q

clozapine monitoring

A

fbc, blood glucose, lipids

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5
Q

amisulpride and furosemide can cause…

A

ventricular arrhythmias

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6
Q

metoclopramide is contraindicated in…

A

pts who have had gastro surgery in the past 3-4 days

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7
Q

24 yr old female thrown up twice in 2 weeks tx

A

metoclopramide 10mg tds

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8
Q

max duration of domperidone

A

7 days

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9
Q

first trimester nausea tx

A

nothing

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10
Q

cyclizine dose in post surgery female

A

50mg tds

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11
Q

how long do the effects of promethazine teoclate work for

A

24 hours

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12
Q

most sedative otc brand for motion sickness

A

phenergan

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13
Q

most suitable for a 6 hour journey otc brand for motion sickness

A

sominex

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14
Q

what percentage of nytol is excreted unchanged in the urine?

A

1%

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15
Q

how long does nytol last?

A

1-3 hours

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16
Q

zimovane side effect

A

dyspepsia - altered taste

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17
Q

what is zopiclone used for

A

insomnia

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18
Q

a contraindication for sumatriptan

A

ischaemic heart disease

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19
Q

what is tolfenamic acid used for

A

acute migraines

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20
Q

topiramate can develop these three conditions

A

acute myopia, secondary angle-closure glaucoma, kidney stones

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21
Q

codeine is contraindicated in…

A

tonsil surgery

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22
Q

paracetamol dose for 3-5 month old

A

60mg every 4-6 hours

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23
Q

paracetamol dose for 6-23 month old

A

120mg every 4-6 hours

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24
Q

paracetamol dose for 2-3 year old

A

180mg every 4-6 hours

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25
Q

paracetamol dose for 4-5 year old

A

240mg every 4-6 hours

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26
Q

paracetamol dose for 6-7 year old

A

240-250mg every 4-6 hours

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27
Q

paracetamol dose for 8-9 year old

A

360-375mg every 4-6 hours

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28
Q

paracetamol dose for 10-11 year old

A

480-500mg every 4-6 hours

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29
Q

paracetamol dose for 12-15 year old

A

480-750mg every 4-6 hours

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30
Q

what is 1st, 2nd and 3rd line for palliative pain?

A

morphine, oxycodone, diamorphine

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31
Q

what would you add if pt was already on paracetamol, ibuprofen, oramorph 2.5mg/2hrs and pain still not controlled?

A

morphine mr 15mg bd - match the daily dose of immediate

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32
Q

what is the dose of iv paracetamol if pt weighs <50kg (mg/kg)

A

15mg/kg

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33
Q

morphine iv dose is ____ of oral daily dose

A

half

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34
Q

oral morphine is a __th of the dose of oral codeine

A

10th

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35
Q

max breakthrough pain is a __th of total daily dose

A

1/6th

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36
Q

sc dose of morphine is a ___ of oral dose

A

half

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37
Q

which antidepressant drug is not suitable for non adherent people

A

venlafaxine

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38
Q

which antidepressant drug cannot be started immediately if pt wants to switch from ssri

A

moclobemide

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39
Q

which antidepressant class interacts with asian diets

A

MAOIs

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40
Q

which drug interacts with alcoholic mouthwash

A

disulfram

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41
Q

which drug to give if pt continues to be at high drinking risk level after 2 weeks?

A

nalmefene

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42
Q

pt is experiencing symptoms of opioid withdrawal - what do you give?

A

lofexidine

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43
Q

varenicline side effect

A

suicidal thoughts

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44
Q

nicorette max no of sprays daily

A

64

45
Q

mins one nicotinell gum lasts

A

30

46
Q

mins one nicorette 15mg inhalator cartridge lasts if used intensely

A

40 if 10mg - 20 mins

47
Q

max number of nicorette microtabs daily

A

40

48
Q

when should you discontinue bupropion?

A

if abstinence is not achieved in 7 weeks

49
Q

what drug is keppra

A

levetiracetam

50
Q

which aed comes in alcohol and sugar free preparation and should sign the back of an rx

A

phenobarbital

51
Q

which aed do you take with food

A

sodium valproate

52
Q

dose of folic acid if pregnant pt is epileptic

A

5mg

53
Q

drug for a seizure lasting more than 5 mins

A

iv lorazepam

54
Q

which aed is taken at night

A

clobazam

55
Q

which aed causes acne

A

phenytoin

56
Q

target range for phenytoin

A

10-20mg/l

57
Q

ratio of phenytoin sodium:phenytoin

A

100:92

58
Q

sodium valproate is contraindicated in…

A

severe hepatic impairment

59
Q

which aed can cause pancreatitis

A

sodium valproate

60
Q

which antibiotic does carbamazepine interact with

A

clarithromycin

61
Q

target range for carbamazepine

A

4-12mg/l

62
Q

how should you titrate carbamazepine slowly

A

increase 100-200mg every 2 weeks

63
Q

carbamazepine decreases…

A

inr

64
Q

primidone undergoes biotransformation into…

A

phenobarbitone and phenylethylmalonamide

65
Q

which aed do you give if you had seizures and porphyria

A

clonazepam

66
Q

sertraline increases risk of bleeding when given with…

A

nsaids

67
Q

which antidepressant interacts with SSRIs

A

st johns wort

68
Q

escitalopram and quinine can cause…

A

ventricular arrhythmias

69
Q

olanzapine and citalopram can cause…

A

dizziness, faint, qt prolongation

70
Q

this antidepressant is safe for mi pts

A

sertraline

71
Q

which antidepressant can cause suicidal thoughts

A

citalopram

72
Q

which antidepressant class can cause this electrolyte imbalance and what symptoms does it cause?

A

SSRI hyponatraemia - drowsiness and confusion

73
Q

which antidepressant if stopped abruptly has the highest risk of withdrawal symptoms?

A

paroxetine

74
Q

this drug should be taken with caution with sodium in diet

A

lithium

75
Q

lithium enhances which drug

A

lisinopril

76
Q

is lisinopril safe for bf

A

no

77
Q

is lithium safe for bf

A

no

78
Q

if pt has high levels of lithium which three drugs should you stop

A

lithium, ace, bendro

79
Q

target range for lithium

A

0.4-1mmol/l

80
Q

4 side effects of lithium

A

blurred vision, convulsions, lack of coordination, muscle weakness

81
Q

if you have alcohol with tca it can cause

A

sleepiness

82
Q

amitriptyline side effect

A

dry mouth

83
Q

which antidepressant has highest fatality in overdose

A

amitriptyline

84
Q

how much time should be left between stopping tcas and starting maoi

A

1 week

85
Q

apomorphine side effect

A

binge eating

86
Q

cabergoline side effect

A

sudden onset of sleep

87
Q

risperidone exacerbates…

A

pd

88
Q

which drug causes fatal liver toxicity

A

tolcapone

89
Q

list three SNRIs

A

venlafaxine, tramadol, duloxetine

90
Q

what is buspirone used for

A

anxiety

91
Q

procyclidine indication

A

acute dystonia (involuntary muscle movements)

92
Q

drug for motion sickness for 3 hr journey 4 yr old

A

kwells kids 150mcg

93
Q

teething first line for 3 months over

A

paracetamol and/or ibuprofen

94
Q

which patch is once a week

A

buprenorphine

95
Q

name 3 tramadol interactions

A

carbamazepine
fluoxetine
terbinafine

96
Q

which drug treats both depression and bipolar

A

lithium

97
Q

scz 1st line

A

chlorpromazine

98
Q

gabapentin titration dose

A

300mg day 1, 600mg day 2, 900mg day 3 then increase in steps of 300mg every 2-3 days

99
Q

which antipsychotic increases appetite

A

olanzapine

100
Q

which two antipsychotics are affected by smoking

A

olanzapine and clozapine

101
Q

lithium concentration is increased by…

A

NSAID

102
Q

phenalizine is a ___ that interacts with _____. Action taken?

A

MAOI. epinephrine. Avoid when pt on MAOI and 14 days after stopping MAOI if stopped for whatever reason.

103
Q

1st line for focal seizures

A

Carbamazepine or lamotrigine

104
Q

First line for tonic clonic seizures

A

SV

105
Q

First line for absence seizures

A

Ethosuximide or sv

106
Q

First line for myoclonic seizures

A

Sv

107
Q

First line for atonic and tonic seizures

A

Sv

108
Q

Night time aeds

A

Lamotrigine
Phenobarbital
Phenytoin

Pre Reg (17 decks)

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