immune system and malignancy

Question 1

cytarabine route of administration

Answer 1

intrathecal

Question 2

why would mesna be co-prescribed

Answer 2

prevent blood in urine

Question 3

ciclosporin can cause which electrolyte disturbance

Answer 3

hyperkalaemia

Question 4

tacrolimus indication

Answer 4

prevent rejection of kidney transplant

Question 5

methotrexate lab tests

Answer 5

lfts, creatinine, fbc

Question 6

in which three scenarios would you stop methotrexate

Answer 6

hospitalised, sepsis, pneumonia

Question 7

minority of increase in risk of breast cancer is caused by…

Answer 7

gene mutations

Question 8

is tamoxifen taken once daily or once weekly

Answer 8

once daily

Question 9

hirsutism is not associated with this cancer

Answer 9

cervical

Question 10

rituximab mechanism of action

Answer 10

monoclonal antibody that binds to cd20 on B cells

Question 11

cisplatin side effect

Answer 11

ototoxicity

Question 12

doxorubicin side effect

Answer 12

cardiotoxicity

Question 13

bleomycin side effect

Answer 13

pulmonary toxicity

Question 14

ciclosporin interactions

Answer 14

statins
macrolides
ccbs

Question 15

ciclosporin should be…

Answer 15

prescribed by brand

Question 16

vinblastine, vincristine route

Answer 16

IV

Question 17

what does hpv vaccine protect against

Answer 17

cervical cancer

Question 18

why is chemo given every 3 weeks

Answer 18

allow pts normal cells to recover before next cycle

Question 19

why is folic acid not given on same day as methotrexate

Answer 19

methotrexate won’t work as well if given on same day

Question 20

neutropenia can cause…

Answer 20

sepsis