endocrine Flashcards

1
Q

which insulin comes in 100 and 200 units

A

insulin degludec

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2
Q

which insulin can be used for weight loss

A

liraglutide

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3
Q

this insulin is contraindicated in severe heart failure

A

liraglutide

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4
Q

class of liraglutide

A

human glucagon peptide 1 analogue

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5
Q

which two diabetic classes causes hypoglycaemia

A

insulin and sulphonylurea

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6
Q

tx for dka

A

iv insulin soluble human (actrarapid) at fixed rate and normal basal insulin

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7
Q

glargine is a…

A

long acting insulin

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8
Q

liraglutide side effect

A

pancreatitis

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9
Q

alcohol with tolbutamide causes…

A

hypoglycaemia

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10
Q

what decreases tolbutamide

A

ginkgo biloboa

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11
Q

name a short acting sulfonylurea

A

tolbutamide

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12
Q

name a long acting sulfonylurea

A

glibenclamide

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13
Q

which drug should be avoided in elderly

A

glibenclamide

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14
Q

which drug is given to diabetics with poor renal function

A

gliclazide

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15
Q

which drug causes hypoglycaemia with sulfonylurea

A

chloramphenicol

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16
Q

what do you do with metformin when it comes to surgery?

A

discontinue 48 hrs before and 48 hrs after

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17
Q

what should you do with metformin if high creatinine but low egfr

A

review

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18
Q

two benefits of metformin

A

helps with insulin resistances issues and helps lose weight

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19
Q

metformin counselling point

A

with food

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20
Q

severe hypercalcaemia tx

A

pamidronate

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21
Q

gliptins should only be continued if…

A

hba1c is reduced by at least 0.5% points within 6 months

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22
Q

what is added as a triple therapy with metformin and sulfonylurea

A

vildagliptin

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23
Q

if a pt is hypoglycaemic at a specific time you add…

A

gliptins

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24
Q

which drug causes hypoglycaemia when added with metformin, sulfonylurea and insulin

A

linagliptin

25
Q

which drug causes pancreatitis and what should you do?

A

alogliptin (abdominal pain? - stop)

26
Q

which drug is intensively monitored and should be reported to MHRA?

A

dapagliflozin

27
Q

which drug causes utis

A

dapagliflozin

28
Q

what to do if you feel dizzy and faint with flozins

A

see gp asap

29
Q

flozins cause…

A

dka

30
Q

dka symptoms

A

n&v, fast + deep breathing, sleepiness

31
Q

which drug is contraindicated in hf

A

pioglitazone

32
Q

pioglitazone can cause…

A

bladder cancer

33
Q

maximum dose for nateglinide

A

180mg tds

34
Q

what do you do if a diabetic is confused, dizzy, tachycardic

A

glucagon

35
Q

hypoglycaemic 10 day old tx not responding to standard tx

A

diazoxide

36
Q

hypoglycaemia symptoms

A

sweating and dizzy

37
Q

hypoglycaemia tx

A

glucagon

38
Q

action to be taken if heartburn with alendronic acid

A

stop until you see gp

39
Q

when do you refer a fungal nail

A

if they are diabetic

40
Q

name a risk factor of acute pyelonephritis

A

kidney stones

41
Q

zolendronic acid se

A

dental pain

42
Q

name two se of prednisolone

A

hyperglycaemia and gastric ulcers

43
Q

after how many years do you reassess alendronic acid

A

5 years

44
Q

blood glucose is <4mmol tx

A

4-5 dextrose tabs, 4+ eat carbs

45
Q

lab test for carbimazole

A

neutrophil count

46
Q

at what age do you prescribe low dose thyroxine

A

50+

47
Q

croup tx

A

dexamethasone

48
Q

levothyroxine 4 side effects

A

weight loss, anxiety, tachycardia, insomnia

49
Q

ulcerative colitis exacerbation tx and dose

A

hydrocortisone 100mg qds iv

50
Q

normal alcohol units and advice

A

14 units a week spread over 3 days or more

51
Q

insulin must be prescribed by brand t/f

A

true

52
Q

what to report - pt taking prednisolone for first time

A

call GP straightaway if any breathless, swelling, vision change, bruising/bleeding, black poo, dark vomit

53
Q

basal is

A

long

54
Q

bolus is

A

short

55
Q

example of basal

A

isophane

56
Q

dose of prednisolone for acute exacerbation of copd

A

40mg daily for five days

57
Q

dose of prednisolone for acute exacerbation of asthma

A

30mg daily for five days

58
Q

hypothyroidism 4 symptoms

A

tired, constipation, weight gain, weakness

59
Q

swallowing too much pool water can cause

A

hyponatraemia