Nervous System Flashcards
What are the 2 types of nervous tissue cells?
1) Neurons
2) Glia
What are neurons?
Specialized cells for generating and propagating impulses across cells
What are glia cells?
Support cells of the NS
What is the basic cell of nervous tissue?
Neurons
What 4 structures make up a neuron?
1) Dendrites
2) Cell body
3) Axon
4) Axon terminal
Where does an axon commonly terminate, and what does it form?
Terminates on a neuron forming a synapse
What is a synapse?
The site of signal transmission between neurons
Most synapses are ______
Chemical
Where are astrocytes found?
White and gray matter
What do astrocytes secrete?
Growth factors
What is the function of astrocytes?
Physical, metabolic, and structural support
What 3 types of cells make up glia?
1) Astrocytes
2) Oligodendrocytes
3) Microglia
What is the function of oligodendrocytes?
Provide myelin sheaths around axons
What are microglia?
Macrophages of the NS
What is the function of microglia?
Protect against viruses, bacteria, and tumor cells
When are microglia cells activated?
During inflammation in the CNS
What 2 types of cells make up the PNS?
1) Schwann cells
2) Satellite cells
What are Schwann cells?
Myelin producing cells of the PNS
What are satellite cells?
Support cells of the PNS found within ganglia
How many pairs of cranial nerves are there and where are they attached?
12 pairs attached to the brain
How many pairs of spinal nerves are there and where are they attached?
31 pairs attached to spinal cord
What does gray matter consist of?
Neuronal cell bodies and dendrites
What is gray matter the site of?
Synaptic connections
What makes up the surface of the brain?
Gray matter
What is a nucleus (CNS)?
A collection of neuronal cell bodies that have a similar function
What does white matter consist of?
Axons
What constitutes the “wiring” of the brain?
White matter
What is a fasciculus?
A bundle of axons of similar functions and connections
What is the corpus callosum?
The largest fasciculus that connects the left and right cerebral hemispheres
What are the 3 main sections of the brain?
1) Forebrain
2) Midbrain
3) Hindbrain
What are 2 main principles of the NS?
1) Bilateral symmetry and “decussations”
2) “Maps” within the brain
What are decussations?
Descending motor tracts that start on the right and cross over to the left
What is the sensory homunculus?
A sensory map of the body in the rain that includes pain, temp., touch, proprioception, and vibration
What is the largest section of the brain?
Forebrain
What is the forebrain divided into?
Telencephalon (cerebrum) and diencephalon
What is the midbrain?
Short, narrow “stalk” that connects forebrain and hindbrain
What 3 sections does the hindbrain consist of?
1) Pons
2) Cerebellum
3) Medulla
What does the telencephalon consist of?
- Cerebral cortex (gray matter)
- White matter (axons)
- Ventricles
- Basal ganglia / nuclei
What are the 4 lobes of the brain?
1) Frontal
2) Parietal
3) Temporal
4) Occipital
What does functional localization mean?
Different sites of the brain have different functions
What does “contralateral nature of motor and sensory cortex” mean?
Left brain corresponds to right brain and vice versa
What is the cerebral cortex connected to?
Thalamus and spinal cord
What does the frontal lobe control?
Movements, behaviour, speech, and decision making
What separates the frontal and parietal lobe?
Central sulcus
What is the site of the primary motor cortex?
Pre-central gyrus
What is the pre-central gyrus responsible for?
Activating motor neurons of the spinal cord on the opposite side of the body
What is the site of the primary somatosensory cortex?
Post-central gyrus
What does the parietal lobe control?
Somatosensory info – pain, temperature, proprioception, and interpretation of sensory input
What separates the parietal and occipital lobes?
Parietoccipital sulcus
What is the site of the primary visual cortex?
Gyri on medial surface of occipital lobe
What is the site of the primary auditory cortex?
Gyri on floor of lateral sulcus of temporal lobe
What is the site of the primary olfactory cortex?
Inferior surface of temporal lobe
What lobe is the hippocampus contained within?
Temporal
What is the function of the hippocampus?
Memory formation
What is the function of basal nuclei?
Regulate motor activity
What is the diencephalon?
Area between cerebrum and midbrain
What does the diencephalon make up?
Thalamus and hypothalamus
What does the diencephalon form and where?
The wall of the 3rd ventricle between the 2 lateral ventricles of the cerebral hemispheres and 4th ventricle
What is the MOTOR function of the diencephalon?
Regulates motor activity via connections with basal nuclei and cerebral cortex
What part of the brain regulates autonomic NS activity?
Hypothalamus
Where is all sensory info (except smell) processed and then where is it relayed?
Processed in thalamus and relayed to cerebral cortex
What 2 cranial nerves are found in the midbrain?
CN 3 (occulomotor) and CN 4 (trochlear)
What is the midbrain the site of?
Substantia nigra and reticular formation
What is the reticular formation important for?
Consciousness and arousal
What makes up the brainstem?
Midbrain, pons, and medulla
What is the largest section of the hindbrain?
Pons
What is the pons made up of?
- Fibres
- Cranial nerve nuclei and RF
- Pontine nuclei
What is the medulla made up of?
- Fibres
- Cranial nerve nuclei (9, 10, and 12)
- Reticular formation
Where is the brainstem located?
Between diencephalon and spinal cord
Where is the brainstem connected to the diencephalon?
Anterior margin of tentorium cerebelli
What 3 things does the brainstem contain?
1) Fibre tracts (white matter)
2) Cranial nerve nuclei (gray matter)
3) Other nuclei related to cerebellar function and consciousness
What is the cerebellum important for?
Maintaining equilibrium and fine motor coordination
What are the 3 membranous layers that cover the brain and spinal cord?
1) Dura mater
2) Arachnoid mater
3) Pia mater
What are the functions of the membranous layers?
Protection and compartmentalization of cranial cavity
What is dura made of?
Collagen
What is dura close to?
Bone
What is arachnoid close to?
Dura
What is the size of the layer of dura in the cranium?
Dense
What is the size of the layer of arachnoid in the cranium?
Thin
What is the thinnest and innermost layer of the membranous layers?
Pia
What kind of space are the cranial epidural and subdural spaces?
A potential space
What is the cranial epidural space inbetween?
Dura and skull
What is the cranial subdural space inbetween?
Dura and arachnoid
What is epidural hematoma?
When the middle meninigeal artery lies between dura and skull, which will leak blood and cause dura to separate from skull
What is subdural hematoma?
When vessles passing between arachnoid and dura leak blood into subdural space
Where is the subarachnoid space?
Between arachnoid and pia
What is the subarachnoid space filled with?
Cerebrospinal fluid (CSF)
Are blood vessels present in the subarachnoid space?
Yes
How many cavities are there in the ventricular system and what are they filled with?
4 cavities filled with fluid
What drains into the 3rd ventricle and through what?
- 2 lateral ventricles
- Through inter-ventricular foramina
What drains into the 4th ventricle and through what?
- 3rd ventricle
- Through midline cerebral aqueduct
What parts of the brain make up the floor of the 4th ventricle?
Pons & medulla
What part of the brain makes up the roof of the 4th ventricle?
Cerebellum
What part of the brain makes up the wall of the 3rd ventricle?
Diencephalon
What is the flow of the ventricular system?
2 lateral ventricles into midline 3rd ventricle, which drains into 4th ventricle via cerebral aqueduct
What does the 4th ventricle drain into?
Subarachnoid space
What produces cerebralspinal fluid?
Choroid plexus