Nervous System Flashcards
basic principles of sensation
- > the afferent division of the peripheral nervous system tells us about out internal and external environment
- > only certain types of energies, or stimulus modalities can be detected by our bodies
- > afferent division of the peripheral nervous system has specialized receptors and transduce stimuli into action potentials, which are relayed to the CNS
general overview
stimulus -> receptor -> neuron -> CNS (receives, interprets and responds)
types of sensory receptors
- > photoreceptors: vision/ light
- > mechanoreceptors: touch
- > chemoreceptors: chemical environment
- > nociceptors: pain
- > thermoreceptors: temperature
- > osmoreceptors: solute concentration and osmotic activity
two classes of sensory receptors
- complex neural receptor (olfaction, somatic senses)
- special senses receptor (vision, hearing, balance, taste)
transduction at complex neural receptor
- application of stimulus
- alteration of receptor membrane (e.g. usually Na+ channels open)
- local current flow within receptor (receptor potential - graded potential)
- change in frequency of action potentials
- AP propagation to central nervous system
transduction at special senses receptor
- application of stimulus
- alteration of receptor membrane (in photoreceptors Na+ channels close in response to light)
- local current flow within receptor (receptor potential - graded potential)
- release of neurotransmitter
- change of post-synaptic membrane potential
- change in frequency of action potentials (AP)
- AP propagation to central nervous system
what about the intensity and duration of the stimulus?
at an individual receptor, a stronger and longer stimulus produces a larger and longer receptor potential
this is transduced into a higher frequency of action potentials that last longer
this leads to the release of more neurotransmitters
action potentials vs receptor potentials
- > action potentials are all-or-none - once initiated, they will flow down the entire axon
- > receptor potentials are graded - they can differ in amplitude and dissipate over time and distance
receptive fields
the part of sensory space that can change the activity of a neuron
smell
- > the receptor cells for olfaction are neurons (primary sensory neurons)
- > the synapse with secondary neurons in the olfactory bulb
how do we perceive different smells?
- > we have about 350 different odor recptors
- > the combination of signals coming from neurons creates the perception of different smells
taste
- > taste is currently believed to be a combination of five sensations: sweet, sour, salty, bitter and umami
- > we have about 2000-5000 taste buds
- > each taste bud contains 50-150 taste cells
- > each taste cell is a non-neural epithelial cell, responsible for taste transduction
important structures of the CNS for sensory physiology
- cerebrum - cortex, basal ganglia, limbic system
- cerebellum
- brain stem - medulla oblongata, pons and midbrain
- diencephlon - thalamus, hypothalamus, pineal gland, pituitary gland
- spinal cord (central nervous system)
cortical anatomy
central sulcus
frontal lobe (movement & cognition)
temporal lobe (hearing, object perpection)
parietal lobe (sensation)
occipital lobe (vision)
lateral sulcus divides frontal and parietal lobe from the temporal lobe
pons communication centre (relays signals)
medulla oblongata regulates nervous system
cerebellum (balance and body position)
smell - brain
stimulus (smell) -> complex neural receptors -> neurons through olfactory bulb -> olfactory cortex
(faster, since it’s close and doesn’t need to travel through thalamus)