Nerve Signaling (Ch. 19) Flashcards
Acetylcholine
- Excitatory and Inhibitory
- Involved in memory
Dopamine
- Mostly inhibitory
- Involved in emotions, mood, and regulating motor control
Epinephrine
- Excitatory or Inhibitory
- Acts as a hormone when decreased by sympathetic neurosecretory cells of the adrenal gland.
Norepinephrine
- Excitatory and Inhibitory
- Regulates sympathetic effectors
- (in the brain) invoked in emotional responses
Gamma-aminobutyric acid (GABA)
- Inhibitory
- Common inhibitory neurotransmitter in the brain
Relative Refractory Period
Period when a neuron can be restimulated with a greater than normal stimulus.
Depolarization
Point on curve during which Na ions move into the axon.
Polarized
State of an unstimulated neuron’s membrane.
Repolarization
Point on the curve during which potassium ions begin to move out of the axon.
Action Potential
Also called a nerve impulse.
Absolute Refractory Period
Period when a neuron cannot be restimulated because it’s sodium gates are open
Na/K pump
- Mechanism by which ATP is used to
move sodium ions out of the cell
and potassium ions into the cell. - Completely restores and maintains
the resting conditions of the neuron
Hyperpolarization
- A voltage change that reduces the
ability of a neuron to conduct an
impulse. - The membrane potential becomes
more negative.
Sequence of events for a nerve impulse
1) Neurotransmitters cross the synaptic
cleft and bind to the receptors on the
postsynaptic membrane.
2) The neurotransmitters cause the Na
channels at the excitatory synapses to
open.
3) Sodium ions flood into the neuron and
make it more positive.
- Depolarization
4) Once the inside of the neuron gets to -55,
the action potential travels down the
axon.
5) Calcium comes into the synaptic bulbs to
push the neurotransmitter vesicles out to
the next neuron.
6) Postassium is pumped out of the cell to
make it more negative again.
- Repolarization
7) The inside of the cell becomes extra
negative (-90).
- Hyperpolarization
8) The cell goes back to normal.