nephron

Question 1

where do potassium sparing diuretics act what cell

Answer 1

potassium sparing diuretics in the aldosterone - sensitive principal cells in the cortical collecting tubule.

Question 2

person has compartment syndrome and muscle death what ion is released due to degree f renal impariemtn

Answer 2

ompartment syndrome, delayed diagnosis and muscle death. The effect of muscle death will result in the release of potassium. It is also highly likely that there will be a degree of renal impairment, the result of which is that the serum potassium is likely to be high.

Question 3

GFR is equal to

Answer 3

equal to the concentration of a solute in the urine, times the volume of urine produced per minute, divided by the plasma concentration (assuming that the solute is freely diffused e.g. inulin)

Question 4

A patient with impaired renal function is prescribed a new medication which is normally eliminated through renal excretion.

Which of the following would you expect to affect excretion of the medication?

Answer 4

Diffusivity across the basement membrane and tubular secretion/reabsorption

Clearance of a substance is dependent on diffusivity across the basement membrane and tubular secretion/reabsorption

Question 5

passage of blood to the nephron

Answer 5

afferent arteriole, glomerular capillary bed, efferent arteriole, peritubular capillaries and medially vasa recta

Question 6

renal blood flow accounts for how much of the cardiac output?

Answer 6

25%

Question 7

insulin is filled but not readkbsorded how do you calculate the renal plasma flow

Answer 7

using clearance equation

Para-aminohippuric acid (PAH ) is used as it is both filtered and secreted

Question 8

renal blood flow is

Answer 8

1-hameocrit

Question 9

horseshoe kidney trapped under what artery

Answer 9

IMA

Question 10

where does phosphate reabsorption occur

Answer 10

PCT

which you suspect is most likely due to the inhibitory effect of parathyroid hormone on renal phosphate reabsorption.