Neoplastic Flashcards
What are other causes of Bronchogenic carcinoma (lung cancer) besides active cigarette smoking?
Asbestos, Radon, passive smoking, genetic oncogenes
Is clubbing of the fingers a sign of possible lung cancer?
yes
What do you need to diagnosis bronchogenic carcinomas?
Tissue biopsy
What are characteristics of a tumor that make it more likely malignant than benign?
1) Fast growing
2) IR borders/ Ill defined margins/ spread throughout
3) Sparse Ca++
4) Cavitary lesion
What is the leading cause of CA death in both men and women?
lung CA
what is the common sx presentation of a pt diagnosed with solitary pulmonary nodule?
Nothing, they are usually ASX
Solitary Pulmonary Nodule: Hallmark Xray finding
<3cm rounded opacity with normal lung surrounding it
Cigarette smoking causes what percentage of lung cancer?
85-90%
What three lung disorders have an increased risk of lung cancer?
pulmonary fibrosis, chronic obstructive pulmonary disease, sarcoidosis
These 5 histologic categories account for 90% of primary lung cancer:
squamous adenocarcinoma adenocarcinoma in situ large cell small cell
Which is the most common type?
Adenocarcinoma, 35-40%, which arise from mucus glands
Which type is prone to early spread and is rarely amenable to surgical resection and have a very aggressive course with a median survival of 6-18 weeks?
Small cell. The non-small cell (NSCLC) types spread slower and can be cured in the early stages with surgery
What is the common signs and symptoms of a lung cancer patient?
NEW COUGH OR CHANGE in chronic cough, dyspnea, anorexia, weight loss, weakness, hemoptysis, digital clubbing, BIG PACK YEAR HISTORY
What paraneoplastic syndromes (precede, during, or follow) occur in lung cancer patients?
small cell - inappropriate antidiuretic hormone
squamous - hypercalcemia
digital clubbing, anemia, hypercoagubility, peripheral neuropathy
T/F. All patients will lung cancer have abnormal findings on CXR or CT scan, especially if isolated nodule.
True, nearly.
