NEOPLASIA Flashcards

1
Q

What is the incidence of neoplasia in the UK

A
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2
Q

what is the mortality rate in the UK regarding neoplasia

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3
Q

what types of tests can you do as. GDP to check for neoplasia

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4
Q

How can neoplasia impact dentistry

A

Dental extractions
Max fax placement
Reconstruction after surgical sections fo tumour
Encounter neoplasia in clinical career

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5
Q

What does Neoplasia mean

A
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6
Q
A
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7
Q

what does Tumour mean

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8
Q

what does Oncology mean

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9
Q

what is the biological definition of a neoplasm

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10
Q

What does persistence of tumour growth after removal of stimulus result from?

A

Cells accumulate genetic alterations
- unregulated growth

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11
Q
A
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12
Q

what does malignant mean

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13
Q

What does benign mean?

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14
Q

what does carcinogenesis require

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15
Q

hallmarks of cancer?

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16
Q

Label these components

A
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17
Q

what causes cancer

A

All have some agent or factor that destabilises the cell cycle

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18
Q

list some oncogenic pathogens

A
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19
Q

list carcinogenic substances

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20
Q

List radiation sources

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21
Q

Is age a factor in tumour development

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22
Q

what is obesity and how is it related to cancer

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23
Q

How could being overweight cause cancer

A
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24
Q

how is inheritance and cancer linked

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25
Q

what is the main distinguishing features of neoplasia

A
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26
Q

what are features of anaplasia

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27
Q

How is well, poor, undifferentiated defined

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28
Q

How is neoplasia classified, graded and stage

29
Q

what is anaplasia

30
Q

Describe these images

31
Q

what is metaplasia

A

Epithelium can change from one cell type to another
Areas of natural transition in the body , for example change from squamous to glandular epithelium at certain sites
Also metaplasia in response to a stimulus
This examples shows changes in the bronchus form columnar to squamous
Barrett’s oesophagus - squamous to glandular in response to acid reflux

32
Q

what is hypertrophy

33
Q

what is hyperplasia

35
Q

what is dysplasia

37
Q

what is carcinoma in situ

A

Invasive malignancy -needs to breach the basement membrane
Barrier that separates the epithelium from the underlying lamina porporia and connective tissue which contains all the soft tissue in vessels
Once it breaches its carcinoma up to that points it dysplasia

38
Q

what should we refer dysplasia to instead of pre malignant (histroric)

A

potential malignant

39
Q

what is the rate of growth

40
Q

Describe bending tumours compared to malignant tumours

43
Q

how are tumours classified

44
Q

describe different types of benign tumours

44
Q

Describe what surface and glandular epithelial are used for

45
Q

what are the rules of naming benign tumours

46
Q

if the benign tumour is form glandular/secreotry/ductal epithelium

47
Q

if bending tumour from non glandular/ non secretory surface epithelium then it is called

48
Q

what is benign epithelial tumours classified as

49
Q

what are malignant epithelial tumours called

50
Q

what are maglignt epithelial tumours derived form glandular ductal epithelium called

51
Q

What is malignant epithelia tumours derived from surface non-glandular epithelial are named by prefixing ………

55
Q

Describe salivary gland tumours

56
Q

what do you call malignant mesenchyme tumours

58
Q

rules of malignant mesenchymal tumours

60
Q

describe examples of other tumours

61
Q

what are teratomas

62
Q

describe precusro cell tumours

63
Q

describe some Brain tumours

64
Q

what is a hamartoma

65
Q

what is the choristoma