Neoplasia

Question 1

Multiple myeloma v lymphoma

Answer 1

Electrophoresis - will see 1 large peak for myeloma

Question 2

Myeloma

Answer 2

Proliferation of neoplastic cells in bone marrow
Signs - non specific (anorexia, lethargy, weight loss, pyrexia, PUPD), hyperviscosity (cerebral dysfunction, ocular changes, CHF), ocular signs of hyperviscosity (retinal haemorrhage/ detachment), bone pain, lameness, bleeding disorders
Mean age onset 8yo

Question 3

Peri-anal adenoma tx

Answer 3

Surgery - removal and castration , radiotherapy, hormonal therapy (deslorelin)
Deslorelin works to suppress testosterone production

Question 4

Castrated male dogs

Answer 4

Prostatic neoplasia (adenocarcinoma? TCC - from bladder but can have prostatic involvement)

Question 5

Benign prostatic hyperplasia tx

Answer 5

Ypozane blocks testosterone
Once a day for a week and then fine for 6 months

OR

castration

Question 6

Anal sac adenocarcinoma

Answer 6

Cocker spaniels predisposed
Constipation?
Malignant spread to lymph nodes rectal and sub iliac (caudal dorsal abdomen not kidneys)
FNA ultrasound guided/ CT and remove affected tissues
Chemo
MST 18 months with treatment