Neoplasia 1 Flashcards
Yolk sac (ectodermal sinus) tumor teratoma
Aggressive malignancy in ovaries (testes in boys) and sacrococcygeal area of young children. Yellow, friable, solid masses. 50% have Schiller-Duval Teratoma bodies (resemble glomeruli). 90% of ovarian germ cell tumors. Contain cells from 2 or 3 germ layers. Mature teratoma (“dermoid cyst”)—most frequent benign ovarian tumor. Immature teratoma—aggressively malignant. Struma ovarii—contains functional thyroid tissue. Can present as hyperthyroidism
Choriocarcinoma
Rare but malignant; can develop during pregnancy in mother or baby. Large, hyperchromatic syncytiotrophoblastic cells. ↑ frequency of theca-lutein cysts. Along with moles, comprise spectrum of gestational trophoblastic neoplasia.
Tumor marker: hCG
Neoplasia
New growth
Tumor
Swelling due to inflammation
Oncology
Oncos is tumor, logy is study
Cancer
Malignant tumors
Parenchyma
Proliferating neoplastic cells
Stroma
Connective tissue and blood vessels
Malignant tumors:
Lymphoma
Mesothelioma
Melanoma
Seminoma
Non-tumors:
Nevus: benign
Hydatidiform mole: benign
Hamartoma: mass of disorganized indigenous tissue
Choristoma: heterotopic rest of cells
Benign Neoplasm
Adenoma
Angioma
Rhabdomyoma
Malignant neoplasm- carcinoma
Squamous cell carcinoma
Adenocarcinoma
Malignant neoplasm- sarcoma
Angiosarcoma
Rhabdomyosarcoma
Tissues of mesenchymal origin- CT and derivatives
Benign Malignant
Fibroma. Fibrosarcoma
Lipoma. Liposarcoma
Chondroma. Chondrosarcoma
Osteoma. Osteogenic sarcoma
Tumors of Endothelial and related tissues: Blood vessels Lymph vessels Synovium Mesothelium Brain coverings
Benign. Malignant
Hemangioma. Angiosarcoma
Lymphangioma. Lymphangiosarcoma
Synovial sarcoma
Mesothelioma
Meningioma. Invasive meningioma
