Molecular Mechanism of CA

Question 0

Mechanisms used by tumors to evade apoptosis

Answer 0

1. Reduced level of FAS
2. Inactivation of FADD
3. Upregulation of BCL2
4. Reduced expression of BAX
5. Loss of APAF1 expression
6. Upregulation of Inhibitors of Apoptosis

Question 1

The two major routes to Apoptosis:

Answer 1

Extrinsic and intrinsic