NEONICOTINOID INSECTICIDES (ACH AGONISTS)

Question 1

NEONICOTINOID INSECTICIDES (ACH AGONISTS)

Answer 1

→ 560x affinity to nACh-receptors of parasites

fastest acting group 
imidacloprid (Advantage family, Foresto)1st gen. 
dinotefuran (Vectra) 3rd gen. 
nitenpyram (Capstar) 1st gen.
ENVIRONMENTAL TOXICITY!

Question 2

Combination

Answer 2

Dinotefuran+permethrin+pyriproxyfen (Vectra 3D spot on A.U.V.)

Question 3

Imidacloprid

Answer 3

(Advantage, Advantix, Advocate, Foresto A.U.V)

One of the most effective agents against fleas, rapid action (within 6 hours >95%)
Fleas, for 4 weeks 
Epithelial debris! 
5-20x overdose is still safe (tremors, seizures?) 
Collar, spot on
\+ permethrin (Advantix) 
\+ flumethrin (Foresto) 
\+ moxidectin (Advocate)