Neonatology Flashcards
What are the normal vital signs for a full term newborn?
Heart rate- 120-160bpm
Resp rate- 30-60 breaths per minute
Blood pressure- 70/44, increases from 1 hour after birth
How can a newborn’s breathing be assessed?
Blood gas determination PaCO2 5-6 kPa, PaO2 8-12 kPa Trans-cutaneous pCO2/O2 measurement Capnography Tidal volume 4-6 ml/kg Minute ventilation: Tidal Volume ml/kg x respiratory rate Flow-volume loop.
What is physiological jaundice in newborns?
Appears on Day of life (DOL) 2-3.
Disappears within 7-10 DOL in term infants and up to 21 DOL in premature infants.
What is the threshold for treatment in jaundice in newborns?
250 bilirubin from 3 days old (less if younger) for phototherapy
350 bilirubin from 3 days old (less if younger) for exchange transfusion
What is the cause of weight loss in the first few days of life?
Shift of interstitial fluid to intravascular
Diuresis
It is normal not to pass urine for the first 24 hrs
What are the complications of small babies?
Perinatal Hypoxia Hypoglycaemia Hypothermia Polycythaemia Thrombocytopenia Hypoglycaemia Gastrointestinal problems Hypertension Reduced growth Obesity Ischemic heart disease
What are the parameters for prematurity and birth weight?
Preterm<37w Extremely preterm <28w Low b/w <2500g Very low b/w<1500g Extremely low b/w<1000g
What is the management of acute respiratory distress syndrome?
Give Mum dexamethasone
Get surfactant to lungs by CPAP with catheter, ET tube if need to ventilate
Give caffeine to stimulate breathing center when trying to get off ventilation
What is bronchopulmonary dysplasia?
Scarring of the lung tissue on X-ray, caused by overstretch or atelectasis-collapse of the lungs
Oxygen has free radicals which are toxic to the tissue then see inflammatory changes (raised WCC, oedema)
Scarring makes the lungs stiff and cant breathe properly-problems later in life
Use dexamethasone if babies still ventilated, need to give these babies more calories as will be using lots of energy trying to breathe
What is the definition of apnoea and what is the management?
Not breathing for more than 20 seconds
Caffeine and CPAP
What is the management of intraventricular haemorrhage?
Prevent with steroids
Treat with drainage and manage symptoms
What is NEC?
Necrotising enterocolitis
Develops in first few weeks of life (round 6 weeks)
Distended abdomen. Oedema, erythema, shiny
On X-ray- air that is produced by the bacteria
Ischemic and inflammatory changes
Necrosis of bowel
Surgical intervention is often required
Conservative management is sometimes possible antibiotics and parenteral nutrition
What is the energy traingle
It encompasses the close relationship between hypoglycaemia, hypothermia and hypoxia in a neonate
What can be a cause of plethora?
Polycythaemia
What is erythema toxicum?
Maculo-papular rash 30 – 70% of normal term neonates. Very rare in the pre-term. Rash fades by end of the first week No treatment needed