Neonatal jaundice Flashcards
1
Q
Physiologic jaundice- Eti
A
- Low UDPGT activity, high red cells, no flora, slow intestinal motility, increased bilirubin circulation
2
Q
Breast feeding jaundice- Eti
A
- Inadequate intake of breast milk/ supplimentation
- Poor enteral intake
3
Q
Breast feeding jaundice- Dx
A
- Establish if milk supply adequate
- Wt loss > 8%, few wet diapers, few stools, short feeding times/ frequency
4
Q
Breast feeding jaundice- Tx
A
Supplementation
5
Q
Breast feeding jaundice- Sx
A
- High unconjugated bilirubin
- High total serum bilirubin
- Jaundice from day 2 to 3 months of age
6
Q
Physiologic jaundice- Sx/ Dx
A
- Visible jaundice > 24 hrs old
- Bilirubin increase <15mg/dl
- Resolves by week 1
7
Q
Physiologic jaundice- Tx
A
- Phototherapy 425-475 nm
8
Q
Hemolytic unconjugated hyperbilirubinemia - Eti
A
- Maternal antibodies (ABO incompatible or rh-isoimmunization)
- Abnormal cell membranes (hereditary spherocytosis)
- Abnormal cell enzymes (G6PD deficiency)
9
Q
Hemolytic unconjugated hyperbilirubinemia - Dx
A
Coombs test
- Postitive = antibody mediated
- Negative = abnormal cells
10
Q
Non-hemolytic unconjugated hyperbilirubinemia - Eti
A
- Hemorrhage
- Polycythemia
- Bowel obstruction
- Breastfeeding
11
Q
Kernicterus- Eti
A
- ## Irreversible brain injury due to chronic hyperbilirubinemia
12
Q
Kernicterus- Sx
A
- Extrapyramidal mvmt disorder
- Gaze abnormality, limitation of upward gaze
- Auditory disturbances
- Dysplasia of tooth enamel
- Auditory neuropathy & dyssynchonicity
13
Q
Kernicterus- Dx
A
- TSB or transcutaneous bilirubin prior to discharge
- Assess feeding, heme sources, wt, hereditary possibilities
14
Q
Kernicterus- Tx
A
- Intensive phototherapy
- Blood transfusion
