Neonatal calf d+

Question 1

name the 8 pathogens which can cause neonatal calf d++

Answer 1

1. rotavirus
2. coronavirus
3. bovine calicivirus
4. bredavirus
5. astrovirus
6. cryptosporidium
7. E coli (ETEC)
8. Salmonella

Question 2

All these viruses are _NA viruses?

Answer 2

RNA

Question 3

how are these pathogens transmitted?

Answer 3

face-poo
adults shed
non D++ calves are multipliers even wo dz
contaminated environment
fomites

Question 4

what is cryptosporidium?

Answer 4

coccidian
v low infective dose!
contaminated water courses
MANY oocysts excreted

Question 5

what age is this neonatal d+?

Answer 5

under 21do

Question 6

what type of e coli is seen in this dz?

Answer 6

ETEC

Question 7

what virulence factors does ETEC have?

Answer 7

heat stable and heat labile toxins which inhibit absorption and increase mucus secretion
adhesion factors

Question 8

how does d+ lead to acidosis?

Answer 8

enterotoxins cause hypersecretion (ETEC + Cholera)
villus damage = malabsorption (viruses and crypto)
loss of Na+ and Cl- and water
inc motility = partially digested food gets to colon = fermentation and acid build up
this leads to osmotic d+
acidosis ensues with DH