Neisseria And Moraxella

Question 1

Neisseira

Gram ____________
Motility?
Catalase
Oxidase
Spores

Answer 1

Gram negtive siplococci
Non motile (twitching motility )
Catalase and oxidase positive
Non sporing

Question 2

Twitching motility is seen in

Answer 2

Neisseira due to type IV pili

Question 3

Cultivation and selective mediaof neosseria

Answer 3

Blood and choclate agar

Thayer Martin Media : contains antibiotics (vancomycin, colistin, Nystatin)
Modified Thayer Martin is M/C used ( vancomycin, colistin, Nystatin , trimethoprim)

Question 4

Transports media for neisseria

Answer 4

Stuarts and Ames

Question 5

N meningitidis
Which serotype is common inindia

Answer 5

Serotype A

Question 6

Carriers of mengicoccus
Transmission
Invasive disease

Answer 6

Nasipharynx

Droplets
Hematogenous spread or olfactory nerve

Question 7

Main risk factor for invasive meningococcus

Answer 7

Terminal complement deficiency (C5-C7)
Travelling to subsaharan African belt
Aspkenia
Hypogamma globulinemia

Question 8

Meningitis clinical features

Meningococcemia

Answer 8

Fever+ vomiting+nausea+neck rigidity+ petechial /purpuric rash (non blanching)

Fever + vom+ nausea + low BP+ tachycardia
DIC + multiprgan failure

Question 9

Complication of meningitis

Answer 9

Necrosis of purpuric lesions
Residual neuro deficits

Waterhouse Friedrichs sx( adrenal hemorrhage)

Question 10

Tx of meningitis

Answer 10

Ceftriaxone + vancomycin

Question 11

Post exposure prophylaxis (vvv imp) of mengitis

Answer 11

Prophylaxis
Adults Ciproflaxacin OD or
. Ceftriaxone OD or
. Rifampicin x 2days

Children. Cenftriaxone OD
. Rifampicin x 2days

Pregnancy. Ceftriaxone once

Question 12

N gonorrhea
Capsule?

Answer 12

Kidney shaped siplococci
Non capsulated

Question 13

Por B typing of N gonorrhea

Answer 13

Por B 1A : disseminated disease
Por B 1B : local GU tract infection

Question 14

Gonorrhea fts

Answer 14

STD
Males: symptomatic
Urethritis, dysuria (purulent dx)

Females : asymptomatic
Cervicits, endometritis

Question 15

Neonates gonrrhea

Answer 15

Purulent conjunctivitis (severe opthalmia neonatorum)

Question 16

Gonococcemia manifestation (DATe ME)

Answer 16

Dermatitis
Arthritis
Tenosynovitis
Meningitis
Endocarditis

Question 17

Gonorrhea antibiotic resistance

Answer 17

Resistance to Beta lactamase (m/c) : altered protein binding, penicilinnase resistant strains

Resistance to FQs

Resistance to Tetracyclins

Question 18

Treatment of choice of gonorrhea

Answer 18

Ceftriaxone

Question 19

Lipo oligosaccharide (virulence factors) is present in

Answer 19

H influenEa
N meningitis
N gonorrhea