NECROSIS: Irreversible Injury

Question 1

refers to the rapid death of a limited portion of an organism and is considered to be the final stage in irreversible degeneration.

Answer 1

necrosis

Question 2

s the term used for the entire process of degeneration and death of cells.

Answer 2

necrobiosis

Question 3

refers to an area of necrosis in which the gross and microscopic architecture of the tissue and some of the cells are recognizable.

Answer 3

Coagulative or Coagulation Necrosis

Question 4

is another morphological type of necrosis and suggests a semi-solid or fluid mass that has been present for some time undergoing self-digestion.

Answer 4

Liquefactive or liquefaction Necrosis

Question 5

is manifested by loss of recognizable
architecture and will contain combinations of
much dark nuclear debris and amorphous
eosinophilic cytoplasmic debris, perhaps mixed
with components of blood clots, hemorrhage,
thrombi and calcification.

Answer 5

Caseous or Caseation Necrosis

Question 6

is distinctive type of necrosis and occurs in the
abdominal cavity or under the skin.

Answer 6

Fat necrosis

Question 7

occurs when saprophytic bacteria grow in necrotic tissue.

Answer 7

gangrene

Question 8

this occurs in necrotized portion of the skin with moisture loss due to evaporation and drainage and presence of saprophytic bacteria. Ischemia is the common cause

Answer 8

dry gangrene

Question 9

Color is usually black, with gas bubbles and may have much hemorrhage and edema in and around the lesion.

Answer 9

wet gangrene

Question 10

a form of coagulative necrosis resulting from a sudden
deprivation of blood supply.

Answer 10

infarct

Question 11

a type of coagulative necrosis in striated muscles
characterized by loss of striations following necrosis

Answer 11

zenker’s necrosis

Question 12

is a shallow area of necrosis confined to epidermis that heals without scarring.

Answer 12

erosison

Question 13

is an excavation of a surface produced by necrosis and sloughing of the necrotic debris and implies involvement of the tissue below the surface layer.

Answer 13

ulcer

Question 14

is a piece of necrotic tissue in the process of separation from viable tissue and implies a process of shedding when used with reference to a surface.

Answer 14

slough

Question 15

an area of liquefactive necrosis of the nervous tissues. Literally means “softening”

Answer 15

malacia

Question 16

an isolated necrotic mass.

Answer 16

sequestrum

Question 17

refers to the deposition of calcium salts in soft tissues. Usually occurs following tissue necrosis

Answer 17

calcification

Question 18

Types of Calcification:

Answer 18

1) DYSTROPHIC CALCIFICATION
2) METASTATIC CALCIFICATION

Question 19

When calcium salts are deposited in damaged cells and tissues.

Answer 19

DYSTROPHIC CALCIFICATION

Question 20

deposition of calcium salts in vital tissues and is always associated with hypercalcemia

Answer 20

METASTATIC CALCIFICATION

Question 21

is a term that describes widespread of deposition of calcium in tissues of individual treated with a calcium sensitizer.

Answer 21

calciphylaxis

Question 22

means self-digestion by the tissues’ enzymes that are present in, or released into, the cytoplasm of the cell after death.

Answer 22

autolysis