Inflammatory Lesions Flashcards
Is the vascular and cellular response of living tissue to injury.
Inflammation
Causes of Inflammation:
- Pathogenic microoorganism
- Chemical injuries
- Mechanical and thermal injuries
- Immune reactions
The toxic and injurious substances produced by microbes
Pathogenic microorganisms
Cornelius Celsus (30BC to 30 AD) formulated the 4 cardinal features of inflammation:
- Rubor = redness
- Tumor = swelling
- Calor = Heat
- Dolor = pain
- Functio laesa - loss of function
Rudolf virchow added no.5
Cornelius Celsus (30BC to 30 AD) formulated the 4 cardinal features of inflammation:
- Rubor = redness
- Tumor = swelling
- Calor = Heat
- Dolor = pain
- Functio laesa - loss of function
Rudolf virchow added no.5
Is caused by vasodilatation
Redness
Results mainly from fluid exudates accumulation consequent to increased vascular permeability.
Swelling
The sensation of ____ is attributable to rapid inflow of warm blood through dilated vessels in an inflamed area.
Heat
Can be due to distension/compression of tissue and factors such as release of vasoactove chemicals
Pain
Can be due to distension/compression of tissue and factors such as release of vasoactove chemicals
Pain
Added to prevent using the parts that hurts.
Loss of function
Added to prevent using the parts that hurts.
Loss of function
The escape of fluids and blood cells from the vascular system into the insterstitial tissue or body cavities
Exudation
a fluid with low protein content and a specific gravity of less than 1.020
transudate
denotes an excess of fluid in the interstitial tissue or serous cavities; it can be either an exudates or a transudates
edema
a purulent inflammatory exudates rich in leukocytes and parenchymal cell debris
pus
Classification of inflammation according to time:
Peracute inflammation - immediately
Acute inflammation - (day 1-3)
Subacute inflammation - (Day 4 - 3 weeks)
Chronic Inflammation - (3 weeks - wks,mths,yrs)
The overall plan for this fluids and cells are:
- to dilute
- to localized
- to destroy
- to remove
Types of inflammatory exudates:
- serous inflammation
- catarrhal inflammation
- fibrinous inflammation
- purulent inflammation
- hemorrhagic inflammation
- granulomatous inflammation
exudates of predominantly serum
serous inflammation
exudates of predominantly mucus
catarrhal inflamation
predominated by fibrin or blood clots
fibrinous inflammation
exudates of predominanted by pus
purulent inflammation
is a localized collection of pus separated from the surrounding tissue by a fibrous capsule
abscess
exudates of predominanted by abundant red blood cells
hemorrhagic inflammation
a case of severe hemorrhagic lobar pneumonia in cattle affected by hemorrhagic septicemia disease caused by
pasteurella multocida B or E
dilation of blood capillaries or sinusoids with abundant red blood cells.
telangiectasis
exudates of predominanted by nodular, caseous lesions
granulomatous inflammation
an infectious virus disease mainly of highly productive cultivated breeds of cows and zebu, caused by a DNA-containing virus closely related to
nodular dermatitis of cattle
Stages of Inflammation:
Acute and chronic inflammation
cardinal signs of inflammation:
- redness (rubor)
- Heat (calor)
- Swelling (tumor)
- Pain (dolor)
- loss of function (functio laesa)
morphologic patterns:
- Exudative
- proliferative
- granulomatous
resolution and repair:
regeneration and scarring
replacement of lost cells with cells of the same type
regeneration
replacement with connective tissue leading to fibrosis
scarring
refers to diffuse inflammation of subcitaneous connective tissues
cellulitis
are accumulation of serous fluid within tissue spaces, typically occuring post injury or surgery.
seroma