Nausea and Vomiting Flashcards
In which patient groups is N+V more common
- women
- under 50
- anxiety
- repeat exposure
Which cytotoxic drugs have a LOW chance of N+V
- Flouracil
- Methotrexate
- Vinca Alkaloids
Which cytotoxic drugs have a MILD chance of N+V
- Doxorubicin
- High Dose methotrexate
Which cytotoxic drugs have a HIGH chance of N+V
- Cisplatin
What is acute Vomiting
within 24 hours of treatment
What is Delayed Vomiting
after 24 hours after treatment
What is anticipatory Vomiting
before treatment
How to prevent ACUTE vomiting in LOW risk patients
Dexamethasone
or
Lorazepam
How to prevent ACUTE vomiting in HIGH risk patients
Ondansetron + Dexamethasone + Aprepitant
How to prevent DELAYED vomiting in HIGH risk patients
Dexamethasone + Aprepitant
How to prevent DELAYED vomiting in MEDIUM risk patients
Dexamethasone + Ondansetron
How to prevent ANTICIPATORY vomiting
Lorazepam
How are Vinca Alkaloids administered
IV only
What happens if you give Vinca Alkaloids Intrathecally (spine)
FATAL