Ciclosporin Flashcards
1
Q
Can you use in pregnancy and breastfeeding
A
NO
2
Q
Mechanism of Action of Ciclosporin
A
suppress cell mediated response
3
Q
What electrolyte imbalances dose Ciclosporin cause
A
- hypomagnaesia
- hyperkalaemia
4
Q
What 4 hyper– does Ciclosporin cause
A
- hyperkalaemia
- hyperglycaemia
- hyperlipidaemia
- hypertenison
5
Q
What dose Ciclosporin impair
A
- kidney
- liver
6
Q
Ciclosporin side effects
A
- skin reactions
- gingival hyperplasia
- hair changes
7
Q
What effect does only the topical version of Ciclosporin cause
A
visual disturbances
8
Q
What are the two interactions of Ciclosporin
A
- Grapefruit juice
- Purple grapefruit juice
9
Q
What should be pre screened before use of Ciclosporin
A
cancer
10
Q
What should you avoid when on Ciclosporin
A
sunlight (UV)
11
Q
How would you monitor drug levels of Ciclosporin in the blood
A
measure only the trough levels
(lowest conc before re adminstration)
12
Q
How would you prescribe and dispense Ciclosporin
A
via BRAND
