Nausea and Emesis Flashcards
1
Q
During vomiting, are sphincters relaxed or contracted?
A
relaxed
2
Q
Where is the vomiting centre in the brain?
A
medulla oblongata
3
Q
Name 3 complications of severe vomiting.
A
- Mallory-Weiss tear
- Loss of gastric protons and chloride leading to hypochloraemic metabolic acidosis, raising pH of blood
- Hypokalaemia
4
Q
Where is the CTZ?
A
Area posterna, outside blood brain barrier
5
Q
What type of anti-emetic is nabilone?
A
A Cannabinoid
6
Q
Give an example of a H1 Receptor antagonist.
A
Cylizine
7
Q
Name 2 dopamine receptor antagonists.
A
Domperidone, metroclopramide
8
Q
What are muscarinic ACh Receptor antagonists often used for?
A
Motion sickness
9
Q
What type of anti-emetic is aprepitant?
A
NK 1 Receptor antagonist
10
Q
What type of anti-emetic is ondasetron?
A
5HT3 Receptor antagonist
