Nature of gene and genome Flashcards

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1
Q

First to use drosophila (fruit flies) for genetic research

A

Thomas hunt morgan

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2
Q

Linkage into nucleic acid polymers

5 ___ and 3 __ group

A

Phosphate
Sugar hydroxyl group

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3
Q

__ rule of DNA base composition whein A= T and G=C

A

Chargaff`

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4
Q

__ is the exterior of DNA molecule, and the __ and interior

A

sugar phosphate backbone
Bases

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5
Q

3 primary function of DNA

A

Storage of genetic infor
Replication and inheritance capability
Expression of genetic message

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6
Q

changes the level of DNA supercoiling

A

Topoisomerases

Type 1- transient break in one strand
Type 2- transient break in both strand

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7
Q

Highly repeated DNA sequences

A

Satellite DNA- short sequences, evolve rapid

Minisatellite DNA- unstable

Microsatellite DNA-shortest sequences, implicate disorders

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8
Q

How are noncoding elements scattered in the genome?

A

grouped into SINEs and LINEs (short-long interspersed elements)

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9
Q

resembles globin genes but are nonfunctional

A

pseudogenes

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10
Q

she suggested genetic elements are capable of moving

A

Barbara Mcclintock

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11
Q

Other term of jumping genes, and its mobile genetic element

A

Transposition, transposable elements

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12
Q

use RNA intermediate which produces complimentary DNA via diverse transcriptase

A

Retrotransposons

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