Central Dogma Flashcards
Genes reside at particular locations on a particular chromosome
Morgan, Sturtevant
They formulated the one gene-one enzyme hypothesis
Beadle and Tatum
What transcribes rRNA (larger RNA), mRNA (small nuclear RNA), tRNA
RNA pol I
RNA pol II
RNA pol III
Trims primary transcripts
RNA processing
RNA polymerase I is assisted by __ to form the ___
GTFs general transcription factors
PIC preinitiation complex
Missing from mature mRNAa, Eukaryotic cells contain this
Intervening sequence
The presence of genes with an intervening sequences are called __
Split genes
siRNA and miRNA are able to pass through here, and is able to connect plant cells to one another
Plasmodesmata
All mature tRNAs have triplet sequence __ ate their 3 prime end
CCA
Eukaryotic cells require at least __ initiation factors comprising a total of more than __ polypeptide chains
12
25
Binding of the second aminoacyl-tRNA to A site requires __, elongation factor EF-Tu
GTPase
responsible for binding aminoacyl tRNA (aa-tRNA) to the ribosome
increases the rate of protein synthesis
polyribosome
4 steps of elongation
Aminoacyl trna selection
Peptide bond formation
Translocation
Releasing the deacylated tRNA
Responsible for 30 % of inherited disorders
Nonsense mutation