Narcotic Analgesics Flashcards
Morphine
Narcotic analgesic- narcotic analogs
Given parenterally due to first pass effect
Codeine
Narcotic analgesic- narcotic analogs
Partial agonist-low anti-nociceptive effects
Given orally
Greater effect on coughing-anti-tussive effect
Heroin
Narcotic analgesic- semisynthetic
Originally to cure morphine addiction
5x stronger than morphine
Hydromorphone
Narcotic analgesic- semisynthetic
10x stronger than morphine
“Dilaudid”
Oxycodone
Narcotic analgesic- semisynthetic
Partial agonist-available in oral form as oxycontin
0.5x as strong as morphine
Fentanyl
Narcotic analgesic- synthetic
80-100x stronger than morphine
Sufentanil
Narcotic analgesic- synthetic
500-600x stronger than morphine
Alfentanil
Narcotic analgesic- synthetic
500-600x stronger than morphine
Remifentanil
Narcotic analgesic- synthetic
500-600x stronger than morphine
Meperidine
Narcotic analgesic- synthetic
.5x as strong as morphine
No pupil constriction
Methadone
Narcotic analgesic- synthetic
Orally effective-liquid
Less euphoric
Given to wean off morphine
Same strength as morphine
Naloxone
Narcotic analgesic antagonist
Opiate receptor blocker
Naloxone-oxycodone combinations exist to make withdrawl easier
Naltrexone
Narcotic analgesic antagonist
Opiate receptor blocker
Methylnaltrexone
Narcotic analgesic antagonist
Opiate receptor blocker
