Naloxone Flashcards
Naloxone- Name
Narcan
Naloxone- Class
Narcotic (Opiate) Antagonist
Naloxone- MoA
Reverses the respiratory depression and CNS sedation of narcotics by competing for opiate receptor sites in the brain
Naloxone- Indications
Known or suspected narcotic overdoses with inadequate respiratory function
Naloxone- Contra
Not be used if patient has adequate respiratory status
Naloxone- S/E
Cardiovascular: tachycardia, hypertension, dysrhythmias
Neurological: tremors/seizures, aggressive/combative
Gastrointestinal: nausea/vomiting
Naloxone- Routes
IV, IO, IM, IN, ET
Naloxone- A. Dose
1.0 – 2.0 mg IV/IM/IN.
Titrate IV dose to adequate respiratory rate and tidal volume.
May repeat dose every 5 minutes as needed
Naloxone- P. Dose
0.1 mg/kg IV/IM/IN.
Titrate IV dose to adequate respiratory rate and tidal volume.
May repeat dose every 5 minutes as needed
Naloxone- EXTRAS
Precautions: Give drug prior to intubation
Prepare to protect patient and EMS personnel due to aggressive/combative personality following rapid reversal of a narcotic overdose
Does not reverse narcotic-induced hypotension
Use with caution in narcotic addicts or chronic pain patients, as Narcan will rapidly reverse the CNS depressant effects of opiods.
Immediate onset when administered IV/IO/IN/ET and 5-10 minutes if administered IM. Either may last 20-30 minutes
Darvon and other synthetic narcotics may require larger dosages to reverse the effects