Morphine Sulfate Flashcards
Morphine Sulfate- Name
MS
Morphine Sulfate- Class
Opioid Narcotic
CNS Depressant
Morphine Sulfate- MoA
Alters pain perception and produces euphoria
Decreases myocardial oxygen demand by decreasing preload (venous pooling due to peripheral vasodilation) and decreasing afterload (decreased systemic vascular resistance due to peripheral vasodilation)
Depresses the CNS by interacting with opiate receptors in the brain
Morphine Sulfate- Indications
Moderate to severe pain
Chest pain of suspected myocardial origin
Pulmonary Edema from CHF with or without chest pain
Burns
Morphine Sulfate- Contra
Altered level of consciousness
Abdominal pain of unknown etiology (relative)
Patients at risk of respiratory depression
Head injury Hypovolemia
Morphine Sulfate- S/E
Cardiovascular: bradycardia, hypotension, (rebound tachycardia/hypertension)
Neurological: sedation, agitation, tremors/seizures, hallucinations
Respiratory: depression, arrest
Gastrointestinal: nausea/vomiting
Morphine Sulfate- Routes
IV, IO, IM, PO
Morphine Sulfate- A. Dose
Pain Relief:
1.0 – 10.0 mg IV/PO titrated to pain relief
or 5.0 – 10.0 mg IM as a single dose only
Pulmonary Edema:
5.0 – 10.0 mg slow IV push (2.0 mg/minute)
Morphine Sulfate- P. Dose
0.1 – 0.2 mg/kg slow IV push (1.0 mg/minute)/PO titrated to pain relief
or 0.2 mg/kg IM
Morphine Sulfate- EXTRAS
Precautions: Morphine Sulfate is an opiate derivative – Naloxone should be available to reverse any severe respiratory side effects
Interactions: Use with caution with patients taking other analgesics, depressants or narcotics
IV/IO/PO will have an onset of 2-5 minutes and IM will have an onset of 5-10 minutes.
Each will last approximately 3-5 hours
May draw 10 mg (1 ml) into a 10 ml syringe and mix with 9 ml of Normal Saline. This creates a 1 mg/1 ml concentration for better control when administering the medication.