Nagel Study Guide Flashcards
different types of native extracts
fresh, liquid, solid
parts of the hollywood method
screen writer, star, supporting actor, behind the scenes cast, director, producer
what is a screen writer
overall concept
what is a star
primary medicinal herb
supporting actor
2nd or co-primary herbs
director
activator or harmonizing herb
behind the scenes cast
supporting backgrounds herbs
producer
form of herbal product
native extract aka complex fractions
The primary soluble portion of phytochemicals removed from the herb by a liquid solvent and or heat and or pressure, used to draw multiple types of compounds out of herb tissue matrix and into solution. Quality at the beginning of product.
types of native extracts
fresh extracts, liquid extracts of dried plant parts, solid extracts
fresh extract
• Fresh juice, Bottled juice, freeze-dried juice, green tincture, mother tincture.
liquid extracts of dried plant parts
- Decoctions, Infusions
- Hydro-alcoholic (tinctures) 1:2 to 1:10
- Spagyric extracts
- Fluid extracts 1 to 1 strength.
solid extract
concentrated standardized with original solvent removed, often 2:1 or higher
simplified fractions
Secondary extracts of complex fractions to concentrate select compounds , specific chemical portions separated from extracts. Focus on quality at the end product not the beginning. Often thought of uniform mediocrity.
♣ Standardized extracts to specific chemical and ratio, 10 to 1 , 50 to 1.
♣ Volatile oils, Steam or solvent extracted.
isolated constituents
o Isolates, Purifiied compounds: phytochemicals that have been separated from their complex natural matrices, single molecular components removed from complex mixture.
♣ Crystalline drug salts
♣ Prescription drugs from natural sources.
Most Complex, Least Processed
Whole Herb
Native Extracts
(Complex Fractions)
least side effects
-Plant part
-Fresh (undried)
-Frozen
-Dried: freeze, shade, sun, oven (heat)
-Fresh extracts: fresh juice, bottles juice (heated), freeze dried juice or spray dried extracts, preserved juice, green (un-dried) tincture (1:2 – 1:5), homeopathic mother tincture (fresh) 1:10
Liquid extracts of dried plant part: decoctions, infusions (hot or cold), tinctures (water and alcohol 1:2 – 1:5), fluid extracts (1:1)
More side effects
Standardized derivatives (concentrated using multiple solvent fractions, 10:1 – 50:1)
• Ex: Ginkgo biloba standard extract, 24/6
• Critical CO2 extracts (new technology)
Fixed (non-volatile) or aromatic (volatile oils)
• Ex: pure Rosemary oil
• Hydrosols
Crystalline drug salts and purified isolated compounds: Ephedrine HCl, Yohimbine HCl, Berberine sulfate
More side effects
Standardized derivatives (concentrated using multiple solvent fractions, 10:1 – 50:1)
• Ex: Ginkgo biloba standard extract, 24/6
• Critical CO2 extracts (new technology)
Fixed (non-volatile) or aromatic (volatile oils)
• Ex: pure Rosemary oil
• Hydrosols
Crystalline drug salts and purified isolated compounds: Ephedrine HCl, Yohimbine HCl, Berberine sulfate
• Know the basic guidelines for preventing possible tincture incompatibilities.
o Solubility and miscibility
o Fresh vs dried
o Polarity: charge
♣ Polar solvent: (most) water → glycerin → ethanol….
♣ Non-polar: fixed oils
o PH
o Precipitation: alcohol %, tannins, mucilage, Eos
♣ diluting alcohol may cause precipitation; keep similar +/- 20%
♣ Alkaloids: precipitate in alkaline, tannic acids, salicylates; more soluble at acid pH
♣ Oils more soluble at alkaline pH; float to top of water
♣ **always shake tinctures
♣ Mucilage, polysaccharide, fiber: polar, water soluble, precipitate in 25%+ alcohol
o Temperature
o Botanical Matrix
o Solvent Used
o Solvent Percentage
• Understand the advantages and disadvantages of tinctures.
o Alcohol:
♣ Adv: natural source, min 25% to preserve, best perservativa & sanitizer, best solvent for 2nd plant constituents, Peripheral circulatory action
• minimal processing, readily absorbed, convenient and versatile
♣ Dis: taste, high glycemic index, safety (kids, alcoholics, etc)
• Compliance issues, cost issues
o Glycerin:
♣ Adv: fair solvent, good preservative, low glycemic index, sweet taste
♣ Dis: unnatural/fat saponification; need 65% to stabilize; diarrhea in 1-2 oz
• Understand the advantages and disadvantages of tinctures.
o Alcohol:
♣ Adv: natural source, min 25% to preserve, best perservativa & sanitizer, best solvent for 2nd plant constituents, Peripheral circulatory action
• minimal processing, readily absorbed, convenient and versatile
♣ Dis: taste, high glycemic index, safety (kids, alcoholics, etc)
• Compliance issues, cost issues
o Glycerin:
♣ Adv: fair solvent, good preservative, low glycemic index, sweet taste
♣ Dis: unnatural/fat saponification; need 65% to stabilize; diarrhea in 1-2 oz
basic cardiovascular herbal activity terms
Cardiotonic, Circulatory stimulant: , Peripheral vasodilator, Hypotensive
basic cardiovascular herbal activity terms
Cardiotonic, Circulatory stimulant: , Peripheral vasodilator, Hypotensive
Cardiotonic
herbs that have a beneficial action on the heart and blood vessels but do not contain cardiac glycosides. Crataegus, Tilia, Allium sativa. Leonurus