N5 - CNS Inf. III (Kuo)

Question 1

Early delay

• Viral DNA polymerase
• Thymidine kinase

Answer 1

Herpesvirus

Question 2

Cell-cell bridges

Answer 2

Herpesvirus

Question 3

Latent infection

Answer 3

Herpesvirus

Question 4

Tzanck Smear

Answer 4

Multinucleated giant cells - Herpesvirus

Question 5

Diagnosis for HSV encephalitis

Answer 5

PCR of CSF

Question 6

HSV-1

Answer 6

Encephalitis (temporal lobe)

Question 7

HSV-2

Answer 7

Meningitis

Question 8

Stomatitis

Answer 8

HSV

Question 9

Gingivostomatitis

Answer 9

Primary herpes

Question 10

Site of viral latency

Answer 10

Trigeminal ganglia

Question 11

Cold sore

Genitals

Answer 11

Recurrent herpes labialis

Question 12

Trigeminal ganglia

Answer 12

HSV-1 latency

Question 13

Lumbar & sacral ganglia

Answer 13

HSV-2 latency

Question 14

HSV encephalitis severely affects

Answer 14

Temporal and inferior frontal lobes

Question 15

reactivation from latency in the geniculate ganglioin

Answer 15

Bell’s Palsy

Question 17

treatment of choice for HSV encephalitis, systemic disease, recurrent genital herpes

Answer 17

Acyclovir

Question 18

used for treating HSV-1 resistant to acyclovir

Answer 18

Foscarnet

Question 19

First step of Acyclovir MOA

Answer 19

herpesvirus-encoded thymidine kinase phosphorylates it

Question 20

Respiratory spread

Answer 20

Varicella zoster virus

Question 21

chickenpox

Answer 21

VZV

Question 22

Dewdrop on a rose petal

Answer 22

Varicella

Question 23

Interstitial pneumonia

Answer 23

Varicella - adults

Question 24

dorsal root or cranial nerve ganglia

thoracic dermatome

Answer 24

herpes zoster/shingles

Question 25

supporting cells of the CNS i.e. astrocytes

Answer 25

CMV

Question 26

oropharynx

Answer 26

CMV initiated infection

Question 27

Infant congenital infections

Answer 27

CMV

Question 28

Immunocompetent adults with CMV

Answer 28

Guillain-Barre Acute brachial plexopathy

Question 29

Organ transplant recipients and AIDS patients with CMV

Answer 29

encephalitis myelitis retinits polyradiculitis

Question 30

Neonate CMV transmission

Answer 30

Transplacental Intrauterine Cervical secretions

Question 31

Adult CMV transmission

Answer 31

Sexual - semen Organ graft Blood transfusion

Question 32

considered sexually transmitted disease

Answer 32

CMV

Question 33

heterophile-negative mononucleosis syndrome

Answer 33

CMV

Question 34

Tx of CMV

Answer 34

Ganciclovir

Question 35

Owl's eye basophilic intranuclear inclusion body In uruine

Answer 35

CMV

Question 36

Arthropod-Borne Viruses (Arboviruses) familes

Answer 36

Flaviviridae (alphavirus) Togaviridae (alphavirus) Bunyaviridae

Question 37

yellow fever virus

Answer 37

Flaviviridae

Question 38

dengue virus

Answer 38

Flaviviridae

Question 39

Colorado tick fever virus

Answer 39

Reoviridae

Question 40

St. louis encephalitis West nile

Answer 40

Flaviviridae

Question 41

North-central states

Answer 41

California virus - Bunyaviridae

Question 42

High mortality

Answer 42

Eastern equine encephalitis virus - Togaviridae

Question 43

Most common arbovirus

Answer 43

West nile

Question 44

Dead end host of arbovirus

Answer 44

Humans Horses

Question 45

Reservoir of arboviruses

Answer 45

Marsh bird

Question 46

Vector of arbovirus

Answer 46

mosquito

Question 47

Arboviruses replicate within its

Answer 47

vector - insect

Question 48

diseases caused by alphaviruses & flaviviruses

Answer 48

Mild systemic disease encephalitis arthrogenic disease hemorrhagic disease

Question 49

Arbovirus - systemic symptoms

Answer 49

Initial viremia

Question 50

Arbovirus- virus reproduction

Answer 50

secondary viremia